Genes differentially methylated in schizophrenia


Step1: select a study

Step2: input genes

or - Input probes

Step2: input probes

Jaffe (191 cases VS 335 controls)
MAD1L1
PTPRN2
AUTS2
NCOA7
CEP97
MGRN1

or - Input probes

cg12969407
cg03072102
cg04962621
cg23997168
cg23220435
cg14797899

Where does this data come from?

We collected DNA methylation results of schizophrenia from 6 studies with 3 brian prefrontal cortex (PFC) researches and 3 blood researches.

PFC studies

  1. Jaffe AE, Gao Y, Deep-Soboslay A, et al. Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex. Nat Neurosci 2016;19:40-7. [PMID: 26619358]
  2. Numata S, Ye T, Herman M, Lipska BK. DNA methylation changes in the postmortem dorsolateral prefrontal cortex of patients with schizophrenia. Front Genet 2014;5:280. [PMID: 25206360]
  3. Wockner LF, Noble EP, Lawford BR, et al. Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients. Transl Psychiatry 2014;4:e339. [PMID: 24399042]

blood studies

  1. Hannon E, Dempster E, Viana J, et al. An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation. Genome Biol 2016;17:176. [PMID: 27572077]
  2. Montano C, Taub MA, Jaffe A, et al. Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study. JAMA Psychiatry 2016;73:506-14. [PMID: 27074206]
  3. Kinoshita M, Numata S, Tajima A, et al. Aberrant DNA methylation of blood in schizophrenia by adjusting for estimated cellular proportions. Neuromolecular Med 2014;16:697-703. [PMID: 25052007]
If you used this data, please cite the reletive reference.