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Genes Identified by expression imputation

Gene	Location^a	Tissue^b	BETA^c	P-value	GVAR^d	Adjusted BETA	Adjusted OR^e
GNL3	chr3:52715172-52728508	Cerebellum	0.037	1.39-e11	0.115	0.012	1.012
THOC7	chr3:63819546-63849579	Cerebellum	-0.113	5.77-e10	0.010	-0.011	0.989
NAGA	chr22:42454358-42466846	Cerebellum	0.122	1.12-e09	0.009	0.011	1.011
TAC3	chr12:57403784-57422667	Cerebellum	-0.868	8.03-e08	0.000	-0.015	0.985
CHRNA2	chr8:27317279-27337400	Cerebellum	-0.016	1.63-e07	0.395	-0.010	0.990
ACTR5	chr20:37377085-37400834	Cerebellum	0.208	3.88-e07	0.019	0.029	1.029
INO80E	chr16:30006615-30017114	Frontal cortex	0.13	7.25-e12	0.009	0.012	1.013
PLPPR5	chr1:99355801-99470449	Frontal cortex	-0.672	2.58-e09	0.006	-0.053	0.948
FAM205A	chr9:34723052-34729464	Frontal cortex	0.043	1.21-e08	0.061	0.011	1.011
AC110781.3	chr7:1878222-1889567	Thyroid	0.342	1.31-e13	0.002	0.014	1.014
IMMP2L	chr7:110303106-111202588	Thyroid	-0.073	7.09-e12	0.046	-0.016	0.984
IGSF9B	chr11:133778459-133826880	Thyroid	-0.024	3.05-e07	0.156	-0.010	0.991
NMRAL1	chr16:4511681-4545764	Thyroid	0.038	4.03-e07	0.060	0.009	1.009
HIF1A	chr14:62162231-62214976	DLPFC	11.13	7.52-e14	0.000	0.148	1.159
TIMM29	chr19:11039424-11040917	DLPFC	11.207	9.27-e14	0.000	0.168	1.183
ST7-OT4	chr7:116593953-116738860	DLPFC	10.17	5.79-e13	0.001	0.318	1.374
H2AFY2	chr10:71812552-71872036	DLPFC	10.962	3.60-e12	0.000	0.191	1.211
STARD3	chr17:37793318-37819737	DLPFC	10.74	5.90-e12	0.001	0.304	1.355
CTC-471F3.5	chr19:40529291-40531409	DLPFC	8.535	1.11-e11	0.000	0.104	1.110
SF3A1	chr22:30727977-30752936	DLPFC	8.651	1.32-e11	0.000	0.083	1.086
ZNF512	chr2:27805897-27858041	DLPFC	10.312	1.32-e11	0.001	0.261	1.298
FURIN	chr15:91411822-91426688	DLPFC	-0.084	2.22-e11	0.022	-0.012	0.988
INHBA-AS1	chr7:41733514-41818986	DLPFC	8.399	2.24-e11	0.000	0.127	1.135
SF3B1	chr2:198254508-198299815	DLPFC	0.099	6.14-e11	0.014	0.012	1.012
EFTUD1P1	chr15:84748920-84795356	DLPFC	-0.092	1.81-e10	0.017	-0.012	0.988
MLH1	chr3:37034823-37107380	DLPFC	2.84	2.10-e10	0.001	0.069	1.071
GATAD2A	chr19:19496635-19619740	DLPFC	-0.044	2.18-e10	0.071	-0.012	0.988
METTL1	chr12:58162254-58166576	DLPFC	9.357	2.23-e10	0.000	0.166	1.181
DMC1	chr22:38914954-38966291	DLPFC	7.229	4.48-e10	0.000	0.130	1.139
RAD51D	chr17:33426811-33448541	DLPFC	7.612	2.11-e09	0.000	0.111	1.117
RERE	chr1:8412457-8877702	DLPFC	2.847	6.32-e09	0.000	0.036	1.037
PCCB	chr3:135969148-136056738	DLPFC	-0.044	2.05-e08	0.054	-0.010	0.990
CLCN3	chr4:170533784-170644824	DLPFC	0.141	2.96-e08	0.005	0.010	1.010
ATG101	chr12:52463758-52471279	DLPFC	8.086	4.90-e08	0.007	0.695	2.005
JRK	chr8:143738874-143763386	DLPFC	0.032	1.25-e07	0.091	0.010	1.010
PTPRU	chr1:29563028-29653325	DLPFC	-0.077	1.60-e07	0.016	-0.010	0.990
MARCKS	chr6:114178541-114184648	DLPFC	0.398	2.05-e07	0.001	0.015	1.015
TCF4	chr18:52889562-53332018	Anterior cingulate cortex	-0.059	5.22-e13	0.051	-0.013	0.987
DGKD	chr2:234263153-234380750	Anterior cingulate cortex	-0.937	2.63-e11	0.001	-0.022	0.979
C1QTNF4	chr11:47611216-47616211	Anterior cingulate cortex	-0.173	1.37-e09	0.010	-0.017	0.983
PITPNA	chr17:1421012-1466110	Anterior cingulate cortex	-0.243	1.77-e07	0.002	-0.010	0.990
FXR1	chr3:180585929-180700541	Caudate basal ganglia	0.439	5.40-e12	0.001	0.017	1.017
ZDHHC1	chr16:67428322-67450736	Caudate basal ganglia	0.354	5.36-e08	0.001	0.011	1.012
PDE4D	chr5:58264865-59817947	Cerebellar hemisphere	0.365	6.81-e11	0.001	0.013	1.013
DRD2	chr11:113280318-113346413	Cerebellar hemisphere	-0.182	2.47-e10	0.004	-0.012	0.988
PITPNM2	chr12:123468027-123634562	Cerebellar hemisphere	-0.065	2.21-e09	0.028	-0.011	0.989
RINT1	chr7:105172532-105208124	Cerebellar hemisphere	0.086	6.32-e09	0.016	0.011	1.011
SRMS	chr20:62172163-62178857	Cerebellar hemisphere	-0.44	3.08-e08	0.001	-0.011	0.989
SETD6	chr16:58549383-58554431	Cerebellar hemisphere	-0.043	1.05-e07	0.054	-0.010	0.990
APOPT1	chr14:104029299-104073860	Cortex	-0.074	1.24-e10	0.026	-0.012	0.988
VSIG2	chr11:124617368-124622134	Cortex	-0.092	6.01-e09	0.013	-0.011	0.989
SDCCAG8	chr1:243419320-243663394	Cortex	-0.069	3.88-e07	0.002	-0.003	0.997
PIK3C2A	chr11:17099277-17229530	Cortex	-0.04	4.04-e07	0.365	-0.024	0.976
AS3MT	chr10:104629273-104661656	Frontal cortex	0.594	5.65-e17	0.001	0.017	1.017
FOXN2	chr2:48541776-48606433	Hippocampus	-0.25	2.65-e07	0.021	-0.036	0.964
RASIP1	chr19:49223844-49243978	Nucleus accumbens basal ganglia	0.055	3.80-e08	0.034	0.010	1.010
TCF23	chr2:27371872-27376378	Nucleus accumbens basal ganglia	-0.076	4.83-e08	0.019	-0.010	0.990
TTC14	chr3:180319918-180335616	Nucleus accumbens basal ganglia	-0.089	4.84-e08	0.013	-0.010	0.990
TYW5	chr2:200794698-200820459	Putamen basal ganglia	-0.08	2.63-e13	0.035	-0.015	0.985
SNX19	chr11:130745331-130786404	Putamen basal ganglia	0.031	1.31-e12	0.179	0.013	1.013
CIART	chr1:150254930-150259505	Putamen basal ganglia	0.09	6.78-e10	0.017	0.012	1.012
SH2D7	chr15:78370150-78397251	Putamen basal ganglia	0.096	7.89-e09	0.013	0.011	1.011
DGUOK	chr2:74153953-74186088	Putamen basal ganglia	0.255	8.26-e08	0.002	0.011	1.011
C12orf76	chr12:110465872-110511491	Putamen basal ganglia	0.031	2.27-e07	0.095	0.010	1.01
LRRC37A	chr17:44370099-44415160	Putamen basal ganglia	-0.035	2.69-e07	0.076	-0.010	0.991
AC005841.1	chr12:2958397-2966213	Pituitary	0.162	3.28-e09	0.005	0.011	1.011
RPS17	chr15:82821158-82824972	Pituitary	0.035	4.03-e08	0.082	0.010	1.010
BTN1A1	chr6:26501449-26510650	Caudate basal ganglia	-0.261	1.67-e22	-	-	-
VARS2	chr6:30881982-30894236	Anterior cingulate cortex	0.075	7.48-e15	-	-	-
HIST1H3H	chr6:27777842-27778314	Putamen basal ganglia	-1.106	3.22-e10	-	-	-
NUDT3	chr6:34247456-34360451	Nucleus accumbens basal ganglia	0.104	6.55-e09	-	-	-
Gene	Location	Tissue	BETA	P value	GVAR	Adjusted BETA	Adjusted OR

Where does this data come from?

Huckins et al. applied dorso-lateral prefrontal cortex (DLPFC) and 12 GTEx-brain predictors to 40,299 schizophrenia cases and 65,264 matched controls for a large transcriptomic imputation study of schizophrenia. They identified 413 genic associations across 13 brain regions. Stepwise conditioning identified 67 non-MHC genes, of which 14 did not fall within previous GWAS loci. We collated these gene set into our database. More details about the gene expression imputation study can be found in the original study (Huckins et al. 2019. Gene Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nature Genetics, 51:659-674. [PMID: 30911161])

^aLocation	-Location was based on hg19 genome assembly.
^bTissue	-12 GTEx-brain eQTL data and CommondMind Consortium (CMC) DLPFC eQTL data were used by the PrediXcan method.
^cBETA	-effect sizes (BETA) refer to predicted GREX in cases compared with controls. Effect sizes and odds ratios are also shown adjusted to ‘unit’ variance in gene expression.
^dGVAR	-genetic variance.
^eOR	-odds ratio..

If you used this data, please cite the original reference. [PMID: 30911161]