Welcome to SZDB

Gene Browser System

Select all Deselect all Print Save

Show entries

Search:

Gene	GWAS^c	Linkage^d	CNV^e	Integrative^f	Diff Methy^g	Diff Exp^h	Exomeⁱ	Brain Exp	GO^j	Total^k


Gene	GWAS^c	Linkage^d	CNV^e	Integrative^f	Diff Methy^g	Diff Exp^h	Exomeⁱ	Brain Exp	GO^j	Total^k
CACNA1C	Yes	No	No	Yes	Yes	No	Yes	Yes(6.19)	Yes	6
FXR1	Yes	No	No	Yes	Yes	Yes	No	Yes(45.80)	Yes	6
TCF7L2	Yes	Yes	No	Yes	Yes	Yes	No	Yes(8.98)	No	6
ABCB9	Yes	No	No	No	Yes	Yes	Yes	Yes(5.91)	No	5
ACTR2	No	No	No	No	Yes	Yes	Yes	Yes(91.89)	Yes	5
AK4	No	No	No	No	Yes	Yes	Yes	Yes(13.55)	Yes	5
ASPHD1	Yes	No	Yes	No	No	Yes	Yes	Yes(26.68)	No	5
BCCIP	No	No	No	No	Yes	Yes	Yes	Yes(26.92)	Yes	5
BCL6	No	No	No	No	Yes	Yes	Yes	Yes(29.50)	Yes	5
CHRM3	Yes	No	No	No	Yes	No	Yes	Yes(12.94)	Yes	5

Gene	GWAS	Linkage	CNV	Integrative	Diff Methy	Diff Exp	Exome	Brain Exp	GO	Total

Showing 1 to 10 of 8,265 entries

Previous1 2 3 4 5…827Next

Notes

^aweighted values	-By default, we set each evidence that support this gene is associated with schizophrenia as value "Yes", and not assocaited with schizophrenia as value "No".
^bBrain Exp	-We downloaded the brain expression data from The Human Protein Atlas (http://v13.proteinatlas.org/, PMID: 24309898). The brain expression data was used to assess whether a gene is expressed in brain tissue. We set FPKM (Fragments Per Kilobase Million) to "5" as the threshold. If FPKM > 5, we set this value as "Yes", otherwise, "No".
^cGWAS	-Whether a gene was identified by PGC2 GWAS (PMID: 25056061) or CLOZUK + PGC2 GWAS (PMID: 29483656). More details please refer to the original publications or "Gene" > "Genes identified by GWAS" in this database.
^dLinkage	-Whether a gene was identified by Linkage and Association studies. More details please refer to "Gene" > "Genes Identified by Linkage and Association study" in this database.
^eCNV	-Whether a gene was affected by CNV (Copy Number Variant) which was reported by Marshall et al. (PMID: 27869829). More details please refer to the original publications or "Gene" > "Genes affected by CNVs" in this database.
^fIntegrative	-Whether a gene was identified by gene expression integrative analysis or gene expression imputation study (PMID: 30911161). More details please refer to the original publication of gene expression imputation study or "Gene" > "Genes identified by integrative analysis" and "Genes Identified by expression imputation" in this database.
^gDiff Methy	-Whether a gene was differentially methylated between schizophrenia cases and healthy controls in frontal cortex region. More details please refer to the original publication (PMID: 26619358) or "Gene" > "Genes differentially methylated in schizophrenia" in this database.
^hDiff Exp	-Whether a gene was differentially expressed between schizophrenia cases and healthy controls in DLPFC (dorsolateral prefrontal cortex) region. More details please refer to the original publication (PMID: 27668389) or "Gene" > "Genes identified by GWAS" in this database.
ⁱExome	-Whether a gene was identified by exome sequencing studies. More details please refer to "Gene" > "Genes Identified by exome sequencing" in this database.
^jGO	-Whether the Gene Ontology (GO) annotation of a gene is related to brain or neuron funciton.
^kTotal	-The total number of "Yes" in this row.