Schizophrenia is one of the most common and severe psychiatric disorders with a heritability estimated to be about 80%. In recent years, significant progress has been made to elucidate the genetic and molecular mechanisms underlying schizophrenia. Previously, we systematically analyzed the genetic data, gene expression data, and other types of data from various schizophrenia researches and deposited these data in SZDB. Here, we released an updated version of a comprehensive database for schizophrenia research, SZDB2.0, which accompanies significant data expansion and feature improvements, as well as functionality optimization. The SZDB2.0 contains various layers of data of schizophrenia researches, such as genetic data, copy number variants (CNVs) data, whole genome/exome sequencing (WGS/WES) data, gene expression data, functional genomics data, and protein-protein interaction data. The SZDB2.0 contains four modules: SNP module, gene module, CNV module and Others module.
1. Wu Y, Li X, Liu J, Luo X-J, Yao Y-G. 2020. SZDB2.0 an updated comprehensive resource for schizophrenia research. Hum Genet, 139:1285-1297.
2. Wu Y, Yao Y-G, Luo X-J. 2017. SZDB: A Database for Schizophrenia Genetic Research. Schizophr Bull, 43(2):459-471.