Genes identified by convergent functional genomics

Symbol	Entrez Id	Position	Location	Description	Type	^aCFG score	Reference	LocusZoom
ADCYAP1	116	chr18:904944..912173	18p11	adenylate cyclase activating polypeptide 1 (pituitary)	protein-coding	4.0	Ayalew et al., 2012
ALDH1A1	216	chr9:75515578..75568233	9q21.13	aldehyde dehydrogenase 1 family, member A1	protein-coding	4.0	Ayalew et al., 2012
ANK3	288	chr10:61786056..62493284	10q21	ankyrin 3, node of Ranvier (ankyrin G)	protein-coding	4.0	Ayalew et al., 2012
BDNF	627	chr11:27676440..27743605	11p13	brain-derived neurotrophic factor	protein-coding	4.0	Ayalew et al., 2012
CD9	928	chr12:6309482..6347437	12p13.3	CD9 molecule	protein-coding	4.0	Ayalew et al., 2012
CNR1	1268	chr6:88849583..88875767	6q14-q15	cannabinoid receptor 1 (brain)	protein-coding	4.0	Ayalew et al., 2012
COMT	1312	chr22:19929263..19957498	22q11.21	catechol-O-methyltransferase	protein-coding	4.0	Ayalew et al., 2012
CPLX2	10814	chr5:175223610..175311023	5q35.2	complexin 2	protein-coding	4.0	Ayalew et al., 2012
DISC1	27185	chr1:231762561..232177018	1q42.1	disrupted in schizophrenia 1	protein-coding	5.0	Ayalew et al., 2012
DRD2	1813	chr11:113280317..113346001	11q23	dopamine receptor D2	protein-coding	4.0	Ayalew et al., 2012
DTNBP1	84062	chr6:15523032..15663289	6p22.3	dystrobrevin binding protein 1	protein-coding	4.0	Ayalew et al., 2012
FABP7	2173	chr6:123100646..123105219	6q22-q23	fatty acid binding protein 7, brain	protein-coding	4.0	Ayalew et al., 2012
GABRB3	2562	chr15:26788693..27018935	15q12	gamma-aminobutyric acid (GABA) A receptor, beta 3	protein-coding	4.0	Ayalew et al., 2012
GAD1	2571	chr2:171673200..171717661	2q31	glutamate decarboxylase 1	protein-coding	4.0	Ayalew et al., 2012
GNB1L	54584	chr22:19775934..19842462	22q11.2	guanine nucleotide binding protein (G protein), beta polypeptide 1-like	protein-coding	4.0	Ayalew et al., 2012
GRIA1	2890	chr5:152870084..153193429	5q31.1	glutamate receptor, ionotropic, AMPA 1	protein-coding	4.0	Ayalew et al., 2012
GRIA4	2893	chr11:105480800..105852819	11q22	glutamate receptor, ionotropic, AMPA 4	protein-coding	4.0	Ayalew et al., 2012
GRIN2B	2904	chr12:13714410..14133022	12p12	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	protein-coding	4.0	Ayalew et al., 2012
GRM5	2915	chr11:88237744..88796816	11q14.3	glutamate receptor, metabotropic 5	protein-coding	4.0	Ayalew et al., 2012
GSN	2934	chr9:124030380..124095120	9q33	gelsolin	protein-coding	4.0	Ayalew et al., 2012
HINT1	3094	chr5:130494875..130501034	5q31.2	histidine triad nucleotide binding protein 1	protein-coding	4.0	Ayalew et al., 2012
HSPA1B	3304	chr6:3305094..3307616	6p21.3	heat shock 70kDa protein 1B	protein-coding	5.0	Ayalew et al., 2012
HTR2A	3356	chr13:47407513..47471169	13q14-q21	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	protein-coding	4.0	Ayalew et al., 2012
KALRN	8997	chr3:123813558..124440036	3q21.2	kalirin, RhoGEF kinase	protein-coding	4.0	Ayalew et al., 2012
KIF2A	3796	chr5:61601989..61682210	5q12-q13	kinesin heavy chain member 2A	protein-coding	4.0	Ayalew et al., 2012
MBP	4155	chr18:74690789..74844774	18q23	myelin basic protein	protein-coding	5.0	Ayalew et al., 2012
MOBP	4336	chr3:39509070..39567859	3p22.1	myelin-associated oligodendrocyte basic protein	protein-coding	4.5	Ayalew et al., 2012
NCAM1	4684	chr11:112831969..113149158	11q23.1	neural cell adhesion molecule 1	protein-coding	4.5	Ayalew et al., 2012
NDUFV2	4729	chr18:9102628..9134343	18p11.22	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	protein-coding	4.5	Ayalew et al., 2012
NR4A2	4929	chr2:157180944..157189287	2q22-q23	nuclear receptor subfamily 4, group A, member 2	protein-coding	4.0	Ayalew et al., 2012
NRCAM	4897	chr7:107788071..108096841	7q31	neuronal cell adhesion molecule	protein-coding	4.5	Ayalew et al., 2012
NRG1	3084	chr8:31496820..32622558	8p12	neuregulin 1	protein-coding	4.0	Ayalew et al., 2012
PDE4B	5142	chr1:66258193..66840262	1p31	phosphodiesterase 4B, cAMP-specific	protein-coding	4.0	Ayalew et al., 2012
PRKCA	5578	chr17:64298926..64806862	17q22-q23.2	protein kinase C, alpha	protein-coding	4.0	Ayalew et al., 2012
RAB18	22931	chr10:27793249..27829099	10p12.1	RAB18, member RAS oncogene family	protein-coding	4.5	Ayalew et al., 2012
RELN	5649	chr7:103112231..103629963	7q22	reelin	protein-coding	4.0	Ayalew et al., 2012
RGS4	5999	chr1:163038396..163046592	1q23.3	regulator of G-protein signaling 4	protein-coding	4.0	Ayalew et al., 2012
SLC1A2	6506	chr11:35272752..35441532	11p13-p12	solute carrier family 1 (glial high affinity glutamate transporter), member 2	protein-coding	4.0	Ayalew et al., 2012
SNAP25	6616	chr20:10199477..10288065	20p12-p11.2	synaptosome associated protein 25kDa	protein-coding	4.0	Ayalew et al., 2012
SYN2	6854	chr3:12045862..12233532	3p25	synapsin II	protein-coding	4.0	Ayalew et al., 2012
TCF4	6925	chr18:52889562..53255860	18q21.1	transcription factor 4	protein-coding	5.0	Ayalew et al., 2012
TNIK	23043	chr3:170780292..171178197	3q26.31	TRAF2 and NCK interacting kinase	protein-coding	4.0	Ayalew et al., 2012
Symbol	Id	Position	Location	Description	Type	CFG score	Reference	LocusZoom

Note:

^aCFG score: CFG score was evaluated by six evidence: 1) Databases; 2) Human postmortem brain gene expression evidence; 3) Human blood and other peripheral tissue gene
                   expression data; 4) Human genetic evidence (association, CNVs, linkage); 5) Animal model brain and blood gene expression evidence; 6) Animal model genetic
                   evidence (transgenic). All six cross-validating lines of evidence (other human data, animal model data) were weighted equally, receiving a maximum of 1 point
                   each (for human genetic evidence: 0.5 points if it is linkage, 0.75 if it is from CNVs, 1 point if it is association). For more details, please refer to the following
                   reference.
Data source: Ayalew et al. Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction. Molecular Psychiatry, 17(9): 887-
                   905(2012).