TPH1

Basic Information

Gene Symbol	TPH1
Entrez Id	7166
Position	chr11:18042084..18062335
Description	tryptophan hydroxylase 1
Gene type	protein-coding

SNP Information

SNP	Position	Alelle	Gene	Annotation	Info	Or	Se	P-value	eQTL	Score^*
rs10488682	11:18062482	A/T	TPH1	near-gene-5	0.986	0.99124	0.0122	0.4727		7
rs10488683	11:18053545	T/C	TPH1	intron	0.994	1.02470	0.0107	0.02203		7
rs10741734	11:18044648	A/G	TPH1	intron	0.997	0.97103	0.0107	0.00592		7
rs10832874	11:18054777	A/G	TPH1	intron	0.983	0.96996	0.0108	0.004756		7
rs10832875	11:18056572	A/G	TPH1	intron	0.992	0.99154	0.0124	0.4912		7
rs10832876	11:18059929	T/C	TPH1	intron	0.992	1.00894	0.0122	0.4662		7
rs11024447	11:18045792	T/G	TPH1	intron	0.704	0.99920	0.0401	0.9848		6
rs11024449	11:18057885	T/C	TPH1	intron	0.992	0.99173	0.0124	0.5027		7
rs1607395	11:18049736	T/C	TPH1	intron	0.994	0.97045	0.0107	0.005149		6
rs169806	11:18059292	T/C	TPH1	intron	0.990	1.03149	0.0107	0.003864		7
rs172423	11:18056225	T/C	TPH1	intron	0.993	1.00924	0.0121	0.4493		6
rs17721739	11:18056360	T/C	TPH1	intron	0.996	1.01035	0.0141	0.4671		7
rs17794760	11:18055920	A/G	TPH1	intron	0.996	0.98866	0.0141	0.4184		7
rs1799913	11:18047255	T/G	TPH1	intron	0.993	1.03056	0.0107	0.005075		7
rs1800532	11:18047816	T/G	TPH1	intron	0.993	1.03087	0.0107	0.004542		7
rs2056246	11:18051446	T/G	TPH1	intron	0.987	1.03159	0.0108	0.003889		6
rs211102	11:18046493	A/G	TPH1	intron	0.990	0.97229	0.0142	0.0474		6
rs211104	11:18054284	A/G	TPH1	intron	0.974	0.98946	0.0123	0.3917		7
rs211105	11:18055304	T/G	TPH1	intron	0.994	1.00955	0.0121	0.4316		6
rs211106	11:18058026	T/C	TPH1	intron	0.973	0.97219	0.0108	0.009234		7
rs211107	11:18058341	A/C	TPH1	intron	0.990	1.03138	0.0107	0.003952		6
rs211108	11:18058662	T/C	TPH1	intron	0.990	1.03149	0.0107	0.00382		6
rs2237907	11:18049193	C/G	TPH1	intron	0.993	1.03066	0.0107	0.004937		5
rs35527095	11:18044640	A/C	TPH1	intron	0.895	0.99233	0.0244	0.7529		7
rs480425	11:18061643	A/T	TPH1	intron	0.985	1.03128	0.0107	0.00411		6
rs508924	11:18060900	A/C	TPH1	intron	0.987	0.96948	0.0107	0.003847		5
rs591556	11:18061400	T/C	TPH1	intron	0.988	0.96938	0.0142	0.02815		7
rs61882465	11:18052740	A/G	TPH1	intron	0.995	1.01045	0.0141	0.4591		6
rs684302	11:18060353	T/C	TPH1	intron	0.988	1.03169	0.0107	0.003618		6
rs685247	11:18060586	T/C	TPH1	intron	0.923	1.02470	0.0113	0.03065		7
rs685249	11:18060587	T/G	TPH1	intron	0.923	0.97599	0.0113	0.03073		7
rs72874057	11:18056010	C/G	TPH1	intron	0.990	0.98837	0.0142	0.4083		6
rs72874061	11:18056013	T/G	TPH1	intron	0.990	0.98797	0.0142	0.395		6
SNP	Position	Alelle	Gene	Annotation	Info	Or	Se	P-value	eQTL	Score^*

Note: RegulomeDB score^*

score	supporting data	score	supporting data
1a	eQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak	6	other
2a	TF binding + matched TF motif + matched DNase Footprint + DNase peak	5	TF binding or DNase peak
1b	eQTL + TF binding + any motif + DNase Footprint + DNase peak	4	TF binding + DNase peak
2b	TF binding + any motif + DNase Footprint + DNase peak	3b	TF binding + matched TF motif
1c	eQTL + TF binding + matched TF motif + DNase peak	1f	eQTL + TF binding / DNase peak
2c	TF binding + matched TF motif + DNase peak	3a	TF binding + any motif + DNase peak
1d	eQTL + TF binding + any motif + DNase peak	1e	eQTL + TF binding + matched TF motif

CNV Information

The gene is not affected by CNV!

eQTL Information