NEK4

Basic Information

Gene Symbol	NEK4
Entrez Id	6787
Position	chr3:52744796..52804965
Description	NIMA-related kinase 4
Gene type	protein-coding

SNP Information

SNP	Position	Alelle	Gene	Annotation	Info	Or	Se	P-value	eQTL	Score^*
rs1029871	3:52797634	C/G	NEK4	missense	0.990	0.94582	0.0108	2.5E-7		1f
rs10780035	3:52764624	T/C	NEK4	intron	0.995	0.94724	0.0108	4.735E-7		6
rs11130323	3:52770277	T/C	NEK4	intron	0.994	1.05792	0.0108	1.654E-7		6
rs112242273	3:52775060	T/C	NEK4	intron	0.633	1.10971	0.0338	0.002041		7
rs112824891	3:52775013	A/G	NEK4	intron	0.996	1.06439	0.0392	0.1115		6
rs112860674	3:52779591	T/C	NEK4	intron	0.969	0.95371	0.0109	0.00001259		6
rs113071416	3:52798148	A/G	NEK4	intron	0.779	0.94535	0.0379	0.1384		6
rs113474502	3:52799138	A/G	NEK4	intron	0.871	1.05190	0.0196	0.009761		7
rs113528713	3:52761094	A/G	NEK4	intron	0.997	1.06407	0.0392	0.1132		7
rs113859860	3:52779133	T/C	NEK4	intron	0.723	0.95590	0.0256	0.07812		7
rs114687381	3:52765949	A/G	NEK4	intron	0.998	1.06994	0.0406	0.09613		5
rs114707129	3:52784207	A/G	NEK4	intron	0.998	0.93407	0.0406	0.09295		6
rs114796738	3:52757046	T/C	NEK4	intron	0.708	1.02562	0.0287	0.3787		7
rs115745575	3:52753308	T/C	NEK4	intron	0.675	0.97064	0.0331	0.3678		6
rs115801090	3:52796662	A/G	NEK4	intron	0.993	1.06887	0.0407	0.1014		5
rs116212265	3:52796674	A/G	NEK4	intron	0.886	0.96957	0.0278	0.2669		7
rs116493126	3:52750325	T/C	NEK4	intron	0.999	0.93323	0.0406	0.089		7
rs12497998	3:52793602	T/C	NEK4	intron	0.988	0.94923	0.0107	1.139E-6		6
rs13061423	3:52790213	T/C	NEK4	intron	0.992	1.05855	0.0108	1.246E-7		6
rs13063138	3:52759254	A/G	NEK4	intron	0.977	0.95619	0.0200	0.02482		7
rs13071584	3:52804487	T/C	NEK4	intron	0.984	1.05496	0.0107	6.316E-7		1b
rs13074853	3:52779801	T/C	NEK4	intron	0.992	1.05232	0.0107	1.825E-6		7
rs13082208	3:52781539	T/G	NEK4	intron	0.993	1.05570	0.0108	4.756E-7		6
rs13082960	3:52785168	A/C	NEK4	intron	0.993	1.05813	0.0108	1.49E-7		6
rs13087538	3:52763453	A/G	NEK4	intron	0.974	0.95695	0.0200	0.02746		7
rs13087772	3:52782274	T/G	NEK4	intron	0.990	1.05485	0.0108	7.866E-7		7
rs13094778	3:52786913	T/C	NEK4	intron	0.909	0.95906	0.0114	0.0002275		6
rs13095332	3:52787242	T/C	NEK4	intron	0.994	0.94677	0.0108	3.762E-7		7
rs138492110	3:52747021	A/G	NEK4	intron	0.690	0.96532	0.0301	0.2413		-
rs138522038	3:52746527	A/G	NEK4	intron	0.659	0.98403	0.0695	0.817		-
rs142045573	3:52760522	T/G	NEK4	intron	0.711	0.94054	0.0669	0.3593		-
rs142295102	3:52747751	A/G	NEK4	intron	0.766	0.94762	0.0620	0.386		-
rs143423464	3:52751817	A/C	NEK4	intron	0.861	0.84713	0.0454	0.0002609		-
rs143815561	3:52762672	C/G	NEK4	intron	0.896	0.94658	0.0246	0.02555		-
rs146892594	3:52769451	T/C	NEK4	intron	0.734	0.93510	0.0428	0.1173		-
rs147076499	3:52796677	T/C	NEK4	intron	0.810	1.06014	0.0438	0.1817		-
rs150863322	3:52793947	T/C	NEK4	intron	0.879	1.16871	0.0458	0.0006614		-
rs151032151	3:52775040	A/G	NEK4	intron	0.996	1.07552	0.0401	0.06944		-
rs17052404	3:52776664	T/C	NEK4	intron	1.000	0.93641	0.0384	0.08724		2b
rs17477867	3:52795973	A/G	NEK4	intron	0.902	0.98472	0.0248	0.5359		7
rs180840318	3:52761093	T/C	NEK4	intron	0.644	0.93969	0.0678	0.3588		-
rs181612199	3:52779975	T/C	NEK4	intron	0.998	0.93426	0.0406	0.09426		-
rs182451717	3:52787103	A/G	NEK4	intron	0.994	0.93960	0.0394	0.114		-
rs190297652	3:52783386	A/G	NEK4	intron	0.754	1.05159	0.0442	0.2546		-
rs191101411	3:52802833	C/G	NEK4	intron	0.991	0.93716	0.0407	0.1105		-
rs191842035	3:52750023	T/C	NEK4	intron	0.668	1.06705	0.0720	0.3673		-
rs192710451	3:52787102	A/G	NEK4	intron	0.995	1.06258	0.0394	0.123		-
rs2072390	3:52780509	A/T	NEK4	intron	0.992	1.05232	0.0107	1.774E-6		6
rs2079929	3:52765646	T/C	NEK4	intron	0.992	0.95056	0.0107	2.121E-6		6
rs2109634	3:52752075	T/G	NEK4	intron	0.991	1.05274	0.0107	1.539E-6		7
rs2159644	3:52774530	T/C	NEK4	intron	0.990	0.95047	0.0107	2.025E-6		6
rs2230534	3:52802402	A/C	NEK4	coding-synon,intron	0.988	1.05982	0.0108	7.512E-8		6
rs2230535	3:52800284	T/C	NEK4	coding-synon	0.988	1.05971	0.0108	7.782E-8		6
rs2268024	3:52803205	T/C	NEK4	intron	0.986	1.05781	0.0108	2.086E-7		7
rs2268025	3:52795224	A/T	NEK4	intron	0.991	1.05707	0.0108	2.739E-7		6
rs2268026	3:52778347	T/C	NEK4	intron	0.994	1.05770	0.0108	1.823E-7		6
rs2286800	3:52778051	T/C	NEK4	intron	0.994	0.94715	0.0108	4.558E-7		7
rs2336543	3:52747673	A/G	NEK4	intron	0.930	1.01867	0.0160	0.2467		6
rs34131802	3:52800979	A/G	NEK4	intron	0.966	0.95609	0.0200	0.02455		7
rs34184137	3:52774017	C/G	NEK4	intron	0.717	0.95619	0.0279	0.1074		5
rs34610878	3:52759169	C/G	NEK4	intron	0.986	0.94554	0.0108	2.077E-7		6
rs34739010	3:52766122	A/G	NEK4	intron	0.992	1.05222	0.0107	1.873E-6		5
rs34918356	3:52753532	T/G	NEK4	intron	0.973	1.05211	0.0108	2.477E-6		7
rs34986855	3:52780205	A/G	NEK4	missense	0.839	0.88648	0.0333	0.0003039		7
rs35212380	3:52752959	C/G	NEK4	intron	0.943	1.06759	0.0109	1.711E-9		6
rs35386691	3:52761570	T/C	NEK4	intron	0.837	0.98354	0.0279	0.5503		7
rs35526119	3:52749334	T/C	NEK4	intron	0.993	0.95009	0.0107	1.627E-6		1f
rs45458298	3:52745924	T/C	NEK4	intron	0.625	1.14385	0.0455	0.003148		7
rs45556336	3:52778572	T/C	NEK4	intron	0.975	1.04498	0.0200	0.02754		7
rs4687549	3:52763954	T/C	NEK4	intron	0.994	1.05570	0.0108	4.983E-7		7
rs4687644	3:52746541	T/G	NEK4	intron	0.993	1.05232	0.0107	1.754E-6		3a
rs4687648	3:52794367	T/G	NEK4	intron	0.981	1.05211	0.0108	2.446E-6		7
rs4687650	3:52800731	A/G	NEK4	intron	0.987	1.05739	0.0108	2.52E-7		7
rs57946083	3:52755586	A/G	NEK4	intron	0.997	0.93838	0.0392	0.1049		3a
rs58528592	3:52755379	C/G	NEK4	intron	1.000	1.06737	0.0385	0.09061		4
rs58564212	3:52801639	A/C	NEK4	intron	0.977	1.06503	0.0392	0.1081		6
rs59638016	3:52771872	T/C	NEK4	intron	0.996	1.06407	0.0392	0.1131		7
rs59869286	3:52779088	A/C	NEK4	intron	0.995	1.07058	0.0384	0.07593		7
rs60058353	3:52778409	A/G	NEK4	intron	1.000	0.93810	0.0385	0.09649		6
rs60770874	3:52750199	T/C	NEK4	intron	1.000	0.93585	0.0385	0.08489		7
rs62255371	3:52747321	A/G	NEK4	intron	0.995	1.05823	0.0107	1.36E-7		6
rs62255396	3:52782839	T/C	NEK4	intron	0.990	0.94630	0.0108	3.041E-7		7
rs6414570	3:52788959	A/G	NEK4	intron	0.931	1.05464	0.0111	1.796E-6		7
rs6445535	3:52771468	T/C	NEK4	intron	0.992	1.05243	0.0107	1.722E-6		6
rs6445536	3:52785183	A/G	NEK4	intron	0.996	1.07197	0.0399	0.0811		7
rs6762788	3:52792311	T/C	NEK4	intron	0.994	0.93810	0.0385	0.09725		7
rs6769720	3:52764350	T/G	NEK4	intron	0.995	0.93072	0.0398	0.07109		5
rs6787154	3:52784416	T/C	NEK4	intron	0.991	0.94999	0.0107	1.573E-6		5
rs72960237	3:52757653	A/G	NEK4	intron	0.997	1.06535	0.0392	0.1066		6
rs72960240	3:52759133	A/C	NEK4	intron	0.997	0.93305	0.0398	0.08219		6
rs72960260	3:52776608	A/T	NEK4	intron	1.000	0.93810	0.0384	0.09655		2a
rs72960274	3:52789943	T/C	NEK4	intron	0.993	1.06460	0.0392	0.1105		6
rs72960281	3:52802871	T/C	NEK4	intron	0.987	1.06919	0.0399	0.09362		6
rs73078847	3:52764787	A/C	NEK4	intron	0.862	1.07004	0.0221	0.002217		5
rs73078853	3:52777753	A/T	NEK4	intron	0.726	1.05707	0.0593	0.3496		6
rs73078856	3:52789754	C/G	NEK4	intron	0.852	1.07090	0.0222	0.00199		6
rs74429279	3:52766257	C/G	NEK4	intron	0.996	0.92941	0.0401	0.06792		6
rs75321479	3:52778210	A/G	NEK4	intron	0.998	0.93473	0.0406	0.09635		6
rs78014137	3:52776778	T/C	NEK4	intron	0.998	0.93473	0.0406	0.09636		4
SNP	Position	Alelle	Gene	Annotation	Info	Or	Se	P-value	eQTL	Score^*

Note: RegulomeDB score^*

score	supporting data	score	supporting data
1a	eQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak	6	other
2a	TF binding + matched TF motif + matched DNase Footprint + DNase peak	5	TF binding or DNase peak
1b	eQTL + TF binding + any motif + DNase Footprint + DNase peak	4	TF binding + DNase peak
2b	TF binding + any motif + DNase Footprint + DNase peak	3b	TF binding + matched TF motif
1c	eQTL + TF binding + matched TF motif + DNase peak	1f	eQTL + TF binding / DNase peak
2c	TF binding + matched TF motif + DNase peak	3a	TF binding + any motif + DNase peak
1d	eQTL + TF binding + any motif + DNase peak	1e	eQTL + TF binding + matched TF motif

CNV Information

The gene is not affected by CNV!

eQTL Information