ITK

Basic Information

Gene Symbol	ITK
Entrez Id	3702
Position	chr5:156607907..156682109
Description	IL2-inducible T-cell kinase
Gene type	protein-coding

SNP Information

SNP	Position	Alelle	Gene	Annotation	Info	Or	Se	P-value	eQTL	Score^*
rs10066955	5:156612468	C/G	ITK	intron	0.971	1.01928	0.0110	0.08117		7
rs10079961	5:156619180	T/G	ITK	intron	0.958	1.00975	0.0175	0.5792		7
rs10475928	5:156608920	A/G	ITK	intron	0.992	0.97814	0.0496	0.6557		7
rs10866648	5:156666039	A/G	ITK	intron	0.986	1.01116	0.0108	0.3037		6
rs113512645	5:156670950	A/T	ITK	intron	0.642	0.99730	0.0560	0.9619		4
rs114626188	5:156620236	T/C	ITK	intron	0.900	1.00833	0.0296	0.7796		6
rs114797179	5:156666260	T/C	ITK	intron	0.848	1.03987	0.0420	0.3518		7
rs12055362	5:156679423	A/G	ITK	intron	0.955	0.98926	0.0170	0.5238		5
rs12187924	5:156612093	T/G	ITK	intron	0.987	0.99581	0.0149	0.775		7
rs12187941	5:156619013	T/C	ITK	intron	0.973	0.99382	0.0125	0.6219		7
rs12518271	5:156608913	T/C	ITK	intron	1.000	1.02501	0.0303	0.4145		7
rs12521028	5:156663119	T/C	ITK	intron	0.978	0.99203	0.0124	0.5161		7
rs13154392	5:156658124	A/G	ITK	intron	0.983	1.01430	0.0331	0.6677		6
rs13156454	5:156624919	T/C	ITK	intron	0.962	0.99870	0.0148	0.9298		7
rs13156643	5:156672719	A/G	ITK	intron	0.989	0.98285	0.0330	0.5997		3a
rs13157017	5:156610285	T/C	ITK	intron	0.891	0.97297	0.0328	0.4038		6
rs13158276	5:156664205	A/G	ITK	intron	0.978	1.00965	0.0119	0.4205		7
rs13158680	5:156658492	A/G	ITK	intron	0.983	1.01400	0.0331	0.6739		6
rs13159987	5:156668109	A/C	ITK	intron	0.991	0.98393	0.0330	0.623		7
rs13163030	5:156658660	T/C	ITK	intron	0.983	1.01430	0.0331	0.6679		7
rs13164045	5:156659494	A/G	ITK	intron	0.983	1.01430	0.0331	0.6676		7
rs13164509	5:156659761	A/G	ITK	intron	0.983	1.01430	0.0331	0.6676		6
rs13164898	5:156652746	A/G	ITK	intron	0.982	1.01349	0.0331	0.6851		5
rs13165100	5:156662410	A/G	ITK	intron	0.983	0.98590	0.0331	0.6679		7
rs13165787	5:156662138	T/C	ITK	intron	0.983	0.98590	0.0331	0.6678		7
rs13168833	5:156669589	T/G	ITK	intron	0.990	0.98373	0.0330	0.6194		7
rs13169497	5:156662775	T/G	ITK	intron	0.983	0.98985	0.0330	0.7569		6
rs13171106	5:156654280	A/C	ITK	intron	0.983	1.01410	0.0331	0.6719		6
rs13174611	5:156663706	T/G	ITK	intron	0.982	0.98629	0.0330	0.6765		5
rs13176569	5:156664174	T/C	ITK	intron	0.982	0.98600	0.0331	0.6705		7
rs13181034	5:156672523	T/C	ITK	intron	0.989	1.01745	0.0330	0.6		4
rs13181664	5:156659721	A/G	ITK	intron	0.983	0.98590	0.0331	0.6679		7
rs13183385	5:156652829	T/C	ITK	intron	0.982	0.98669	0.0331	0.6849		7
rs13183539	5:156652911	T/C	ITK	intron	0.982	0.98669	0.0331	0.6848		7
rs13184646	5:156610983	T/G	ITK	intron	0.991	0.99402	0.0149	0.6878		7
rs13187882	5:156674627	A/G	ITK	intron	0.971	1.02081	0.0332	0.5345		5
rs13190139	5:156670024	A/C	ITK	intron	0.990	1.01654	0.0330	0.6188		7
rs13190673	5:156671873	A/C	ITK	intron	0.954	0.98432	0.0142	0.2673		7
rs13355489	5:156664822	T/C	ITK	intron	0.987	1.00491	0.0146	0.7387		5
rs13357051	5:156664899	T/G	ITK	intron	0.835	1.02768	0.0373	0.4643		6
rs13361568	5:156664955	T/C	ITK	intron	0.954	1.00070	0.0171	0.9686		7
rs140958911	5:156671102	T/C	ITK	intron	0.861	1.05527	0.0409	0.1889		-
rs141369568	5:156616520	A/G	ITK	intron	0.977	0.96948	0.0507	0.5416		-
rs142437652	5:156672104	A/G	ITK	intron	0.847	0.95954	0.0421	0.326		-
rs146658958	5:156661805	A/G	ITK	intron	0.843	0.94337	0.0627	0.3524		-
rs152105	5:156619470	A/G	ITK	intron	1.010	0.97326	0.0301	0.3675		7
rs152119	5:156616410	C/G	ITK	intron	0.982	1.00260	0.0117	0.8231		4
rs163311	5:156617851	C/G	ITK	intron	0.996	0.96705	0.0155	0.03096		6
rs163312	5:156617837	T/C	ITK	intron	0.983	0.99820	0.0106	0.8627		7
rs163313	5:156617814	T/C	ITK	intron	0.996	0.96696	0.0155	0.03035		6
rs163314	5:156617679	A/G	ITK	intron	0.996	0.96705	0.0155	0.03085		6
rs163315	5:156617587	T/G	ITK	intron	0.996	0.96705	0.0155	0.03076		7
rs163317	5:156616696	A/C	ITK	intron	0.976	1.00331	0.0106	0.7584		7
rs163318	5:156616488	T/C	ITK	intron	0.972	0.99830	0.0107	0.8702		5
rs163426	5:156621767	T/C	ITK	intron	0.995	1.03925	0.0168	0.02178		7
rs163427	5:156622166	T/C	ITK	intron	0.987	0.99611	0.0106	0.7151		7
rs163428	5:156622245	T/C	ITK	intron	0.988	1.00381	0.0106	0.7172		7
rs163429	5:156622286	A/G	ITK	intron	0.988	1.00391	0.0106	0.7151		6
rs163430	5:156622520	A/G	ITK	intron	0.988	0.99611	0.0106	0.7123		7
rs163431	5:156622572	A/G	ITK	intron	0.988	0.99621	0.0106	0.7226		7
rs17054345	5:156626241	C/G	ITK	intron	0.940	0.97765	0.0155	0.1447		6
rs17054386	5:156669068	A/G	ITK	intron	0.853	0.97142	0.0352	0.4096		6
rs17054397	5:156680876	A/G	ITK	untranslated-3	0.992	0.99114	0.0164	0.5854		3a
rs17575222	5:156617534	A/C	ITK	intron	0.955	0.99730	0.0187	0.8837		7
rs17595788	5:156669423	A/G	ITK	intron	0.951	1.01593	0.0142	0.2668		6
rs17595865	5:156670823	A/G	ITK	intron	0.878	0.99631	0.0213	0.8616		4
rs17654767	5:156673937	T/G	ITK	intron	0.859	1.02071	0.0300	0.4945		6
rs2421470	5:156651721	A/G	ITK	intron	0.965	0.98975	0.0149	0.4891		7
rs2421525	5:156617283	T/C	ITK	intron	0.979	1.00220	0.0123	0.8566		6
rs2431105	5:156620766	A/G	ITK	intron	0.998	0.96754	0.0164	0.04427		7
rs2434973	5:156613641	T/C	ITK	intron	0.994	1.03790	0.0159	0.01932		7
rs2434974	5:156613720	A/C	ITK	intron	0.981	1.03915	0.0162	0.01768		7
rs2436382	5:156619818	A/G	ITK	intron	0.989	0.99780	0.0120	0.8515		6
rs2436383	5:156620013	C/G	ITK	intron	0.989	0.99581	0.0106	0.6941		7
rs2436384	5:156620451	T/C	ITK	intron	0.990	1.00411	0.0106	0.6992		7
rs25775	5:156671918	A/G	ITK	intron	0.992	0.98718	0.0120	0.2813		7
rs25776	5:156673225	T/C	ITK	intron	0.982	1.01379	0.0121	0.2557		5
rs25855	5:156624400	A/G	ITK	intron	0.988	1.00411	0.0130	0.7539		6
rs27341	5:156679576	T/C	ITK	intron	0.979	1.00975	0.0108	0.37		5
rs28638168	5:156658941	A/G	ITK	intron	0.951	1.00080	0.0171	0.961		7
rs30112	5:156655718	T/C	ITK	intron	0.975	0.99253	0.0128	0.5578		7
rs30114	5:156652929	C/G	ITK	intron	0.999	0.98570	0.0120	0.2311		7
rs30115	5:156622376	A/G	ITK	intron	1.000	0.97297	0.0304	0.3673		7
rs30117	5:156664978	T/C	ITK	intron	0.996	1.00070	0.0115	0.9548		6
rs31221	5:156625898	T/G	ITK	intron	0.713	0.95600	0.0668	0.5006		5
rs31222	5:156625548	A/G	ITK	intron	0.940	0.97795	0.0109	0.04095		4
rs34051542	5:156662093	T/C	ITK	intron	0.983	1.01430	0.0331	0.6676		7
rs34056240	5:156657105	A/T	ITK	intron	0.983	0.98590	0.0331	0.6675		7
rs34064633	5:156665266	A/T	ITK	intron	0.990	1.01674	0.0330	0.6147		6
rs34099004	5:156671000	T/C	ITK	intron	0.948	0.98364	0.0142	0.2452		5
rs34184802	5:156665268	A/C	ITK	intron	0.990	1.01674	0.0330	0.6146		7
rs34207706	5:156661855	T/C	ITK	intron	0.983	1.01430	0.0331	0.6676		6
rs34289242	5:156659697	A/G	ITK	intron	0.983	1.01430	0.0331	0.6675		6
rs34366200	5:156653374	T/G	ITK	intron	0.982	0.98649	0.0331	0.6816		7
rs34449697	5:156655145	A/G	ITK	intron	0.979	0.98521	0.0331	0.6515		6
rs34471719	5:156656888	A/C	ITK	intron	0.983	1.01430	0.0331	0.6681		6
rs34583711	5:156652239	A/G	ITK	intron	0.982	0.98679	0.0331	0.6871		7
rs34585804	5:156652169	T/C	ITK	intron	0.982	1.01339	0.0331	0.6876		7
rs34906042	5:156657682	A/G	ITK	intron	0.983	1.01430	0.0331	0.6681		6
rs34980806	5:156653932	T/C	ITK	intron	0.982	1.01390	0.0331	0.6759		6
rs35037141	5:156652428	C/G	ITK	intron	0.982	1.01339	0.0331	0.6871		7
rs35178394	5:156659084	A/G	ITK	intron	0.983	0.98590	0.0331	0.6681		5
rs35238137	5:156658234	T/G	ITK	intron	0.983	1.01420	0.0331	0.6691		5
rs35474823	5:156653687	A/C	ITK	intron	0.982	1.01379	0.0331	0.6782		7
rs35485660	5:156653455	A/G	ITK	intron	0.982	1.01369	0.0331	0.6809		6
rs35601391	5:156667798	T/C	ITK	intron	0.991	0.98393	0.0330	0.623		7
rs35608043	5:156653402	C/G	ITK	intron	0.982	0.98649	0.0331	0.6816		6
rs35654903	5:156658899	A/G	ITK	intron	0.983	1.01430	0.0331	0.6677		7
rs35668839	5:156653866	T/G	ITK	intron	0.982	0.98629	0.0331	0.6768		6
rs35732681	5:156659014	A/T	ITK	intron	0.983	0.98590	0.0331	0.668		6
rs35737161	5:156653742	A/G	ITK	intron	0.982	1.01379	0.0331	0.6778		6
rs35820140	5:156656400	A/G	ITK	intron	0.983	0.98600	0.0331	0.6691		6
rs35881189	5:156654903	T/C	ITK	intron	0.983	0.98600	0.0331	0.671		7
rs35936741	5:156655400	T/C	ITK	intron	0.983	1.01420	0.0331	0.6701		7
rs35963904	5:156659711	T/C	ITK	intron	0.983	1.01430	0.0331	0.6677		7
rs36028699	5:156661835	A/C	ITK	intron	0.983	0.98590	0.0331	0.6678		7
rs36089357	5:156656463	T/C	ITK	intron	0.983	0.98600	0.0331	0.6692		7
rs365171	5:156606311	T/C	ITK	near-gene-5	0.996	0.96175	0.0159	0.01402		5
rs367153	5:156610846	T/C	ITK	intron	0.995	0.96271	0.0159	0.0168		7
rs3892245	5:156680629	A/C	ITK	untranslated-3	0.992	1.00541	0.0164	0.7441		4
rs3909924	5:156626237	A/G	ITK	intron	0.919	0.97697	0.0135	0.08583		6
rs394378	5:156612088	T/C	ITK	intron	0.995	1.03832	0.0159	0.01787		7
rs407059	5:156612248	A/G	ITK	intron	0.971	0.96580	0.0155	0.02444		7
rs407660	5:156611820	A/G	ITK	intron	0.996	0.96696	0.0155	0.03014		7
rs409602	5:156608284	A/T	ITK	intron	0.997	0.96387	0.0155	0.01774		7
rs411174	5:156609000	A/G	ITK	intron	0.999	0.97922	0.0114	0.06607		6
rs4122648	5:156656955	T/C	ITK	intron	0.982	0.99223	0.0124	0.5266		6
rs4122649	5:156656827	T/G	ITK	intron	0.981	0.99293	0.0123	0.5659		7
rs421286	5:156606123	A/G	ITK	near-gene-5	0.995	0.96377	0.0157	0.0192		5
rs421459	5:156612641	A/G	ITK	intron	0.994	0.96300	0.0158	0.01714		7
rs450067	5:156655015	T/G	ITK	intron	0.956	0.98147	0.0118	0.1123		6
rs451494	5:156606196	A/G	ITK	near-gene-5	0.998	1.03562	0.0155	0.02403		5
rs4704741	5:156666699	A/G	ITK	intron	0.984	0.99561	0.0146	0.7646		7
rs4704856	5:156652152	T/G	ITK	intron	0.977	0.99322	0.0147	0.6408		7
rs4704857	5:156666350	A/G	ITK	intron	0.931	0.97648	0.0284	0.4003		6
rs59681833	5:156679029	A/G	ITK	intron	0.903	0.99950	0.0154	0.9745		6
rs66943334	5:156670916	T/C	ITK	intron	0.951	0.98423	0.0142	0.262		4
rs6860090	5:156667280	A/G	ITK	intron	0.984	0.99541	0.0146	0.7502		5
rs6876898	5:156670047	A/G	ITK	intron	0.978	0.99671	0.0123	0.7869		6
rs6895925	5:156666163	T/C	ITK	intron	0.972	0.99332	0.0110	0.5444		7
rs71591322	5:156653512	A/G	ITK	intron	0.982	0.98649	0.0331	0.6802		7
rs71591324	5:156654986	A/G	ITK	intron	0.983	1.01420	0.0331	0.6709		7
rs71591325	5:156655925	T/G	ITK	intron	0.983	0.98600	0.0331	0.6698		7
rs71591326	5:156655952	A/G	ITK	intron	0.967	0.98659	0.0328	0.6819		6
rs71591327	5:156655958	A/G	ITK	intron	0.983	0.98600	0.0331	0.6696		6
rs71591328	5:156656058	T/C	ITK	intron	0.983	0.98600	0.0331	0.6694		7
rs71591329	5:156656142	A/T	ITK	intron	0.983	0.98600	0.0331	0.6693		6
rs71591330	5:156656258	A/G	ITK	intron	0.983	1.01420	0.0331	0.6693		7
rs71591331	5:156657528	T/G	ITK	intron	0.983	1.01430	0.0331	0.6688		6
rs71591333	5:156664492	T/C	ITK	intron	0.961	0.98965	0.0324	0.7479		6
rs71591335	5:156668179	C/G	ITK	intron	0.966	1.00753	0.0122	0.5391		6
rs72807039	5:156614640	A/G	ITK	intron	0.987	1.02296	0.0497	0.6471		4
rs72807040	5:156615302	A/G	ITK	intron	0.987	0.98128	0.0495	0.7026		7
rs73300194	5:156610789	C/G	ITK	intron	0.999	1.02583	0.0302	0.3989		6
rs74464254	5:156678776	C/G	ITK	intron	0.948	1.02347	0.0331	0.4823		7
rs74732059	5:156652029	A/G	ITK	intron	0.982	0.98679	0.0331	0.6878		7
rs75320134	5:156679259	T/C	ITK	intron	0.920	0.99074	0.0185	0.6143		6
rs75760314	5:156680074	A/G	ITK	untranslated-3	0.961	0.97726	0.0327	0.4815		4
rs76212209	5:156658104	T/C	ITK	intron	0.823	0.98020	0.0434	0.6447		7
rs76239251	5:156593436	A/G	ITK	near-gene-5	0.868	1.08698	0.0367	0.02295		6
rs76556455	5:156656784	T/C	ITK	intron	0.974	1.00692	0.0324	0.8304		7
rs76688684	5:156614697	A/G	ITK	intron	0.867	0.97103	0.0432	0.4972		4
rs77323274	5:156676743	T/G	ITK	intron	0.938	1.02245	0.0335	0.5071		6
rs77812008	5:156651983	A/G	ITK	intron	0.982	0.98679	0.0331	0.6874		6
rs78231029	5:156622516	T/C	ITK	intron	0.832	0.93342	0.0410	0.0927		7
rs78796115	5:156659466	T/C	ITK	intron	0.983	1.01430	0.0331	0.6677		6
rs78969277	5:156617894	T/C	ITK	intron	0.964	1.00341	0.0186	0.8558		7
rs79101970	5:156660694	T/C	ITK	intron	0.833	1.03821	0.0487	0.4411		7
rs79627475	5:156681049	A/G	ITK	untranslated-3	0.964	0.97756	0.0327	0.488		5
rs79834934	5:156656785	A/G	ITK	intron	0.983	0.98590	0.0331	0.6686		7
rs9313491	5:156621905	C/G	ITK	intron	0.988	0.98089	0.0109	0.07667		6
SNP	Position	Alelle	Gene	Annotation	Info	Or	Se	P-value	eQTL	Score^*

Note: RegulomeDB score^*

score	supporting data	score	supporting data
1a	eQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak	6	other
2a	TF binding + matched TF motif + matched DNase Footprint + DNase peak	5	TF binding or DNase peak
1b	eQTL + TF binding + any motif + DNase Footprint + DNase peak	4	TF binding + DNase peak
2b	TF binding + any motif + DNase Footprint + DNase peak	3b	TF binding + matched TF motif
1c	eQTL + TF binding + matched TF motif + DNase peak	1f	eQTL + TF binding / DNase peak
2c	TF binding + matched TF motif + DNase peak	3a	TF binding + any motif + DNase peak
1d	eQTL + TF binding + any motif + DNase peak	1e	eQTL + TF binding + matched TF motif

CNV Information

The gene is not affected by CNV!

eQTL Information