Basic Information
Gene SymbolXRCC3
Entrez Id7517
DescriptionX-ray repair complementing defective repair in Chinese hamster cells 3
Gene typeprotein-coding
SNP Information

There is no SZ(PGC) snp in this gene!

CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation
KEGG pathway annotationhsa03440; Homologous recombination
GO annotation
GO pathway annotationGO:0000150; recombinase activity
GO pathway annotationGO:0000400; four-way junction DNA binding
GO pathway annotationGO:0000707; meiotic DNA recombinase assembly
GO pathway annotationGO:0000722; telomere maintenance via recombination
GO pathway annotationGO:0000724; double-strand break repair via homologous recombination
GO pathway annotationGO:0000784; nuclear chromosome, telomeric region
GO pathway annotationGO:0003690; double-stranded DNA binding
GO pathway annotationGO:0003697; single-stranded DNA binding
GO pathway annotationGO:0005515; protein binding
GO pathway annotationGO:0005524; ATP binding
GO pathway annotationGO:0005634; nucleus
GO pathway annotationGO:0005654; nucleoplasm
GO pathway annotationGO:0005657; replication fork
GO pathway annotationGO:0005737; cytoplasm
GO pathway annotationGO:0005739; mitochondrion
GO pathway annotationGO:0006281; DNA repair
GO pathway annotationGO:0006302; double-strand break repair
GO pathway annotationGO:0006310; DNA recombination
GO pathway annotationGO:0006974; cellular response to DNA damage stimulus
GO pathway annotationGO:0007131; reciprocal meiotic recombination
GO pathway annotationGO:0008094; DNA-dependent ATPase activity
GO pathway annotationGO:0008821; crossover junction endodeoxyribonuclease activity
GO pathway annotationGO:0010033; response to organic substance
GO pathway annotationGO:0010212; response to ionizing radiation
GO pathway annotationGO:0010824; regulation of centrosome duplication
GO pathway annotationGO:0033063; Rad51B-Rad51C-Rad51D-XRCC2 complex
GO pathway annotationGO:0033065; Rad51C-XRCC3 complex
GO pathway annotationGO:0042148; strand invasion
GO pathway annotationGO:0045003; double-strand break repair via synthesis-dependent strand annealing
GO pathway annotationGO:0048471; perinuclear region of cytoplasm
GO pathway annotationGO:0071140; resolution of mitotic recombination intermediates
GO pathway annotationGO:0090267; positive regulation of mitotic cell cycle spindle assembly checkpoint
GO pathway annotationGO:0090656; t-circle formation
Co-expression Information

There is no gene co-express this gene!

Expression pattern
Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction