OTUD7B

Basic Information
Gene SymbolOTUD7B
Entrez Id56957
Positionchr1:149912231..149982686
DescriptionOTU deubiquitinase 7B
Gene typeprotein-coding
SNP Information

SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*
rs104942601:149943784T/COTUD7Bintron1.0001.007530.01430.60047
rs104942611:149968717A/GOTUD7Bintron0.9991.040600.02110.059277
rs104943631:149909495A/GOTUD7Bnear-gene-51.0000.958010.02120.043254
rs1112330951:149962986A/GOTUD7Bintron0.6171.091550.04150.034867
rs1112816361:149954805A/GOTUD7Bintron1.0000.958290.02120.044696
rs112053071:149954498A/GOTUD7Bintron0.9990.960600.02110.056437
rs1120583761:149922148A/GOTUD7Bintron0.6841.008330.02930.77656
rs1126892541:149966402C/GOTUD7Bintron1.0000.958290.02120.044736
rs1128526251:149930367T/COTUD7Bintron0.9990.957150.02130.039417
rs1133218281:149975071A/GOTUD7Bintron0.9910.957050.02140.040677
rs1135626341:149967291A/GOTUD7Bintron1.0000.958290.02120.044886
rs1152765211:149932587A/GOTUD7Bintron0.8671.061940.05570.28056
rs1156506951:149982478T/COTUD7Bintron,untranslated-50.9680.956190.01940.020984
rs1160553991:149918338T/COTUD7Bintron0.9960.957720.02120.041956
rs1166534401:149972740A/GOTUD7Bintron0.8921.021220.03120.50077
rs1167099211:149945483A/GOTUD7Bintron0.7240.966570.02830.22947
rs120237481:149941228A/GOTUD7Bintron1.0001.020920.01250.096147
rs120265001:149945558A/COTUD7Bintron1.0000.992630.01430.60686
rs120484931:149927034A/COTUD7Bintron0.7590.997500.01290.84797
rs120776231:149970096C/GOTUD7Bintron0.9991.040910.02110.057082b
rs120810821:149971085A/GOTUD7Bintron0.9991.040910.02110.05715
rs120826891:149972358A/GOTUD7Bintron1.0001.021530.01250.088487
rs1407099951:149928114T/COTUD7Bintron0.9261.053590.02340.02556-
rs1428258191:149928988C/GOTUD7Bintron0.9951.045500.02140.03717-
rs1433678161:149975090C/GOTUD7Bintron0.8461.071110.02840.01544-
rs1437789061:149928679A/GOTUD7Bintron0.9961.022350.01250.07671-
rs1441909051:149925832T/COTUD7Bintron0.6590.953900.06160.4437-
rs1459521271:149946276T/COTUD7Bintron0.7791.037490.05100.47-
rs1500442091:149947809A/GOTUD7Bintron1.0000.958390.02120.04501-
rs1508418111:149924980A/TOTUD7Bintron0.8230.931370.02760.009893-
rs1829176601:149919630T/GOTUD7Bintron0.6761.066730.04600.1604-
rs1867842471:149929245A/GOTUD7Bintron0.7300.913570.03200.004682-
rs1888772011:149925173T/COTUD7Bintron0.8320.939980.02690.02165-
rs1914946551:149924994T/COTUD7Bintron0.6801.002400.04130.9533-
rs1926147731:149925174A/COTUD7Bintron0.8320.939980.02690.02165-
rs20448911:149951811A/GOTUD7Bintron0.9991.041020.02110.056785
rs21981941:149948993T/COTUD7Bintron0.9990.960600.02110.056656
rs352307441:149932039A/COTUD7Bintron0.9990.960600.02110.057036
rs357861751:149951467T/GOTUD7Bintron0.6691.001500.02310.9495
rs39369521:149978552A/GOTUD7Bintron0.9990.979120.01250.090526
rs412651721:149913562T/COTUD7Buntranslated-30.9130.984620.03050.61067
rs412651851:149921839T/COTUD7Bintron1.0000.958290.02120.044887
rs49263991:149924299T/COTUD7Bintron0.9230.983240.01290.18997
rs49264001:149931541A/GOTUD7Bintron0.9980.991540.01430.55147
rs618075521:149919726T/COTUD7Bintron0.7970.985010.04120.71417
rs618075551:149955086A/GOTUD7Bintron0.6900.987180.02050.53166
rs618075561:149955256A/GOTUD7Bintron0.7941.003810.04280.92987
rs65877231:149922960T/COTUD7Bintron0.8201.010560.01170.36937
rs65877291:149926987T/COTUD7Bintron0.9120.989850.01570.51766
rs66824951:149922694T/GOTUD7Bintron0.9691.050960.02180.022816
rs66849871:149929342A/GOTUD7Bintron0.9961.022040.01250.079587
rs674505391:149981884T/COTUD7Bintron0.9870.957910.01940.026874
rs716226691:149933579T/COTUD7Bintron0.7190.997600.03350.94295
rs716226701:149939247T/COTUD7Bcoding-synon0.7150.996510.03350.91744
rs726928231:149910775T/COTUD7Bnear-gene-50.9841.007730.01430.58987
rs726928251:149920593A/COTUD7Bintron0.7320.912110.03140.0033997
rs726928261:149949971A/GOTUD7Bintron0.7010.901050.03390.0020817
rs726928301:149956134T/COTUD7Bintron0.6371.042690.03190.18996
rs730081951:149933006T/COTUD7Bintron0.9991.040600.02110.059125
rs747743091:149971213T/COTUD7Bintron1.0000.958290.02120.044746
rs754805921:149971967T/GOTUD7Bintron1.0001.043620.02120.044436
rs770158461:149943157A/GOTUD7Bcoding-synon,missense1.0000.958200.02120.044196
rs788719121:149977961T/COTUD7Bintron0.7410.969570.02650.2446
rs791174011:149962417T/COTUD7Bintron0.6091.047390.04010.24865
rs793196201:149961601T/COTUD7Bintron1.0000.958290.02120.044867
rs799415891:149956248T/GOTUD7Bintron1.0000.958290.02120.044776
SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*

  Note: RegulomeDB score*
score supporting data score supporting data
1aeQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak6other
2aTF binding + matched TF motif + matched DNase Footprint + DNase peak5TF binding or DNase peak
1beQTL + TF binding + any motif + DNase Footprint + DNase peak4TF binding + DNase peak
2bTF binding + any motif + DNase Footprint + DNase peak3bTF binding + matched TF motif
1ceQTL + TF binding + matched TF motif + DNase peak1feQTL + TF binding / DNase peak
2cTF binding + matched TF motif + DNase peak3aTF binding + any motif + DNase peak
1deQTL + TF binding + any motif + DNase peak1eeQTL + TF binding + matched TF motif
CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation

There is no pathway information about this gene!

GO annotation
GO pathway annotationGO:0000122; negative regulation of transcription from RNA polymerase II promoter
GO pathway annotationGO:0002385; mucosal immune response
GO pathway annotationGO:0003677; DNA binding
GO pathway annotationGO:0004843; ubiquitin-specific protease activity
GO pathway annotationGO:0005515; protein binding
GO pathway annotationGO:0005634; nucleus
GO pathway annotationGO:0005737; cytoplasm
GO pathway annotationGO:0006955; immune response
GO pathway annotationGO:0008234; cysteine-type peptidase activity
GO pathway annotationGO:0008270; zinc ion binding
GO pathway annotationGO:0032717; negative regulation of interleukin-8 production
GO pathway annotationGO:0035871; protein K11-linked deubiquitination
GO pathway annotationGO:0043124; negative regulation of I-kappaB kinase/NF-kappaB signaling
GO pathway annotationGO:0070530; K63-linked polyubiquitin binding
GO pathway annotationGO:0070536; protein K63-linked deubiquitination
GO pathway annotationGO:0071108; protein K48-linked deubiquitination
GO pathway annotationGO:0071947; protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO pathway annotationGO:1900181; negative regulation of protein localization to nucleus
GO pathway annotationGO:1990380; Lys48-specific deubiquitinase activity
Co-expression Information

There is no gene co-express this gene!

Expression pattern
Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction