NTF3

Basic Information
Gene SymbolNTF3
Entrez Id4908
Positionchr12:5541280..5604465
Descriptionneurotrophin 3
Gene typeprotein-coding
SNP Information

SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*
rs1016103312:5599646T/CNTF3intron0.9931.013190.01060.21655
rs1049209512:5561200T/CNTF3intron1.0000.995010.01150.65986
rs1073504912:5553503A/GNTF3intron0.9621.000700.01440.96117
rs1073505012:5558306C/GNTF3intron0.9890.988660.01130.31147
rs1074468112:5554192C/GNTF3intron0.9650.999400.01440.9686
rs1074468212:5555040A/GNTF3intron0.9991.038940.01130.00075697
rs1074468312:5567381A/CNTF3intron0.9951.001600.01760.9297
rs1074468412:5572371C/GNTF3intron1.0001.004010.01310.76217
rs1077432712:5551065A/GNTF3intron0.9681.025210.01400.075125
rs1077432812:5552669T/CNTF3intron0.9571.035930.01110.0014197
rs1077432912:5554678T/GNTF3intron0.9821.001100.01430.94027
rs1077433012:5557893A/GNTF3intron0.9950.987480.01120.26415
rs1077433112:5558518T/CNTF3intron0.9870.988860.01130.32185
rs1077433212:5563162A/GNTF3intron1.0001.011360.01280.37755
rs1077433312:5563167A/GNTF3intron1.0000.989060.01280.39235
rs1077433512:5622664A/GNTF3intron0.8780.980490.03200.5387
rs1077433612:5626158A/GNTF3intron0.9660.978040.01080.040655
rs1077433712:5626326C/GNTF3intron0.9660.978530.01080.045412b
rs1077433812:5628214T/GNTF3intron0.9040.983930.03090.60067
rs1077433912:5630281A/GNTF3intron0.9680.991440.01080.42745
rs1084926812:5542307C/GNTF3intron0.9350.976480.01360.080532b
rs1084926912:5542534T/CNTF3intron0.9410.980300.01350.14075
rs1084927012:5552281T/CNTF3intron0.9521.034790.01110.0019837
rs1084927112:5555120A/GNTF3intron1.0001.060670.02180.0069937
rs1084927212:5559111A/GNTF3intron0.9041.034900.03640.34646
rs1084927312:5568171T/CNTF3intron1.0100.993920.01300.64046
rs1084927412:5574011T/GNTF3intron0.9840.995910.01300.75487
rs1084927512:5583939A/GNTF3intron0.9830.983340.01260.18087
rs1084927612:5594103A/GNTF3intron1.0001.009440.01060.37185
rs1084927712:5603935T/CNTF3coding-synon0.9250.988570.01440.42337
rs1084928012:5628804A/GNTF3intron0.9811.018060.01070.093647
rs1106367512:5546466T/CNTF3intron0.8170.931930.05750.22055
rs1106367712:5551632A/GNTF3intron0.8781.009140.01310.48392b
rs1106367812:5551642T/CNTF3intron0.8670.978530.01970.26954
rs1106367912:5552126A/CNTF3intron1.0000.941580.02080.0038567
rs1106368312:5557207T/GNTF3intron0.9911.018980.01450.19397
rs1106368612:5564541T/GNTF3intron0.9931.015320.01380.27034
rs1106368812:5567145T/CNTF3intron0.9761.008940.01060.40517
rs1106368912:5567146A/GNTF3intron0.9710.993620.01350.63827
rs1106369012:5567925T/CNTF3intron0.9810.952660.02690.071085
rs1106369112:5571448T/GNTF3intron0.9980.982160.01380.19055
rs1106369212:5571845A/CNTF3intron1.0100.995410.01300.72546
rs1106369912:5587152T/GNTF3intron1.0001.030150.01140.009397
rs1106370012:5587753T/CNTF3intron0.9890.968800.01150.0058717
rs1106370112:5587754A/GNTF3intron0.9911.033450.01160.0044947
rs1106370212:5588018A/GNTF3intron0.9980.971420.01150.011595
rs1106370312:5589409A/GNTF3intron0.9971.011470.01060.28145
rs1106370712:5594325A/CNTF3intron1.0000.990640.01060.3736
rs1106370812:5594403T/CNTF3intron1.0000.990350.01060.35937
rs1106371312:5603602C/GNTF3coding-synon0.6411.008030.05090.87486
rs1106371412:5604933A/GNTF3near-gene-30.8980.989550.03590.76986
rs1106372612:5625393T/GNTF3intron0.9460.998300.01240.89287
rs1106372712:5630471A/CNTF3intron0.9450.991830.01430.56527
rs11125343312:5575639A/GNTF3intron0.7960.991830.03850.83195
rs11205577512:5599756T/CNTF3intron0.7641.021430.04830.66165
rs11208196812:5579370A/GNTF3intron0.9130.975990.04010.54367
rs11350380512:5547233A/CNTF3intron0.8861.070370.03120.02947
rs11687267612:5599397A/GNTF3intron0.8651.068870.04060.10115
rs11689637012:5556269T/GNTF3intron0.8761.061200.03960.13347
rs11736667112:5588227T/GNTF3intron0.9170.903030.04670.028936
rs11739769412:5565515A/CNTF3intron0.8681.075300.03870.060835
rs11740402412:5552112A/GNTF3intron0.9301.039560.03510.26956
rs11762525412:5623325T/CNTF3intron0.8480.966470.04300.42875
rs11765320712:5546853T/GNTF3intron0.9450.992730.02470.7685
rs11787149212:5625791A/GNTF3intron0.7541.037590.02560.14976
rs11802082412:5600325T/CNTF3intron0.8781.012070.03780.75147
rs11811847212:5588541A/GNTF3intron0.8510.959730.05210.435
rs1183622112:5541891A/GNTF3intron0.8470.993720.01160.58685
rs1183622212:5541892A/CNTF3intron0.8470.993720.01160.58685
rs1229844212:5591819A/GNTF3intron0.9911.008940.01060.40055
rs1230691812:5593727C/GNTF3intron0.9981.029840.01510.050915
rs1231965012:5588971A/CNTF3intron0.9730.977070.01550.13545
rs1236935012:5577867A/GNTF3intron0.9951.000300.01110.97577
rs1237096912:5578655A/GNTF3intron0.9900.998800.01110.91627
rs1242485612:5573613A/TNTF3intron0.9850.989060.01130.32985
rs1281004712:5621572T/GNTF3intron0.9421.001400.01270.90995
rs1281718812:5567619A/GNTF3intron0.9981.004510.01150.69475
rs13857295212:5545191T/GNTF3intron0.7220.986100.06500.8299-
rs13946231112:5570601A/GNTF3intron0.9731.038210.05360.4841-
rs14012669712:5579567A/GNTF3intron0.8451.000800.05650.9886-
rs14120644312:5600070A/GNTF3intron0.7010.954180.04850.3335-
rs14136468912:5602097T/CNTF3intron,near-gene-50.6010.890390.07310.1121-
rs14151195312:5589824A/GNTF3intron0.9370.966090.04320.4235-
rs14151564412:5628605A/GNTF3intron0.8220.988170.04090.7707-
rs14275723712:5569219A/CNTF3intron0.8800.941200.04540.182-
rs14577483112:5564031A/GNTF3intron0.9670.967730.05390.5429-
rs14859096012:5541171A/GNTF3near-gene-50.8130.992830.02640.7857-
rs15070137312:5552639A/GNTF3intron0.7010.962910.05390.4834-
rs1693348912:5572210T/CNTF3intron0.8790.977650.02690.39997
rs1718085112:5554548A/TNTF3intron0.9890.982650.01450.22877
rs1718091312:5560158T/CNTF3intron0.9771.017450.01450.2327
rs1772263212:5571981T/CNTF3intron0.9981.005720.01150.61987
rs1778453312:5550738A/GNTF3intron0.9921.035720.01780.049244
rs1778461112:5575027T/CNTF3intron0.9580.965220.01140.0018687
rs1778463512:5577559A/GNTF3intron0.9811.023060.01270.072467
rs180059912:5540045A/CNTF3near-gene-50.8280.960600.02070.052632b
rs180514912:5603607A/GNTF3missense0.6481.007020.05190.89266
rs18070274212:5541132C/GNTF3near-gene-50.7521.043940.03020.1547-
rs18129414212:5575333T/CNTF3intron0.8291.154540.06400.02474-
rs18601575812:5578071A/TNTF3intron0.9780.977850.05480.6827-
rs18917349312:5540835A/CNTF3near-gene-50.7050.922650.05010.1077-
rs19108113112:5561399T/CNTF3intron0.7950.970450.05100.557-
rs19263863912:5576551A/GNTF3intron0.8151.074660.05690.2057-
rs205235512:5576943A/GNTF3intron0.9891.003310.01640.84197
rs3413624712:5576366A/GNTF3intron0.8010.966090.03490.3237
rs3435222112:5576371T/GNTF3intron0.7670.935850.03970.094827
rs3436818712:5594593T/CNTF3intron1.0001.009550.01060.37065
rs3448575612:5594627T/CNTF3intron1.0000.990840.01060.38675
rs3479237612:5576369T/CNTF3intron0.7670.935760.03970.094077
rs3491634212:5587483T/GNTF3intron0.9951.032620.01150.0053255
rs3500757312:5594598T/CNTF3intron1.0000.991040.01060.39475
rs3569154412:5594993T/CNTF3intron1.0000.990540.01060.37175
rs3585216612:5557527A/GNTF3intron0.9841.038730.02690.15736
rs3593480212:5594722A/GNTF3intron1.0000.990540.01060.37145
rs389079212:5596415A/GNTF3intron0.9981.029940.01510.050547
rs392402712:5595435A/GNTF3intron1.0001.009340.01060.37725
rs407304212:5628932A/CNTF3intron0.9900.981470.01060.078535
rs407496712:5600466T/GNTF3intron0.9920.978530.01520.15297
rs407747012:5596812T/CNTF3intron1.0001.008940.01060.39837
rs407747112:5596993T/CNTF3intron0.9951.009440.01060.37667
rs476581512:5564909A/GNTF3intron0.9981.003710.01750.83145
rs493076712:5597381T/CNTF3intron0.9941.003510.01060.73845
rs493080612:5630381A/GNTF3intron0.9771.012980.01720.45226
rs493081712:5597017A/GNTF3intron0.9991.009950.01060.34797
rs493081812:5597091T/GNTF3intron0.9990.990050.01060.3437
rs493082012:5597205A/TNTF3intron0.9990.989750.01060.3315
rs5991827712:5588592T/GNTF3intron1.0001.030250.01140.0092425
rs6139471912:5561649T/GNTF3intron0.9650.997400.01420.85457
rs6153406712:5544998A/GNTF3intron0.9500.966180.01700.042547
rs6190767412:5560017T/CNTF3intron0.9600.993220.01130.5526
rs6190769912:5569573T/CNTF3intron0.9961.016540.01380.23465
rs6190770012:5574297A/GNTF3intron0.8471.017550.04480.69755
rs6190770112:5576225A/GNTF3intron0.9111.011260.01330.39927
rs6190770212:5583021T/CNTF3intron0.9330.977070.02050.25697
rs6190770312:5583022A/GNTF3intron0.9600.992630.01310.57287
rs648962412:5579631A/GNTF3intron0.9781.015210.01250.22985
rs648962512:5585151A/GNTF3intron0.9821.016740.01260.18766
rs648962612:5588951T/CNTF3intron0.9800.976380.01100.030145
rs648962712:5588999T/CNTF3intron0.9791.015820.01260.21165
rs648962812:5596346T/CNTF3intron1.0001.009550.01060.37017
rs648962912:5601929A/GNTF3intron,near-gene-50.9481.024500.01860.19414
rs648963012:5604624T/CNTF3near-gene-30.9671.002500.01350.85275
rs648963112:5622140T/CNTF3intron0.8650.985210.03000.61817
rs6649771012:5550338T/CNTF3intron0.9880.964450.01790.04324
rs6685613812:5549572C/GNTF3intron0.9810.963870.01790.040287
rs6739472012:5547759T/GNTF3intron0.9601.040290.01790.027456
rs6752367912:5549203A/GNTF3intron0.9780.963580.01800.039115
rs6800506012:5549863A/GNTF3intron0.9840.964060.01790.041215
rs713480112:5588672A/GNTF3intron0.9720.981380.01390.17477
rs7145994712:5540540C/GNTF3near-gene-50.8391.000800.02360.97355
rs7145994912:5573773C/GNTF3intron0.9340.970540.01560.055056
rs7153285012:5602650A/GNTF3intron,near-gene-50.8160.938290.04870.19087
rs7265345212:5600735T/CNTF3intron0.7030.986990.03650.72075
rs730061312:5596141A/GNTF3intron1.0000.990540.01060.37015
rs7303236012:5562104A/CNTF3intron0.8990.972490.02650.29295
rs7303440412:5582560A/GNTF3intron1.0001.025520.01290.050346
rs7303440712:5587317A/TNTF3intron0.9970.969670.01520.04256
rs7303996212:5544625A/GNTF3intron0.9521.040500.01810.028285
rs7303996612:5545532A/GNTF3intron0.9550.961370.01810.029295
rs7303997112:5547096T/CNTF3intron0.9650.962140.01810.032885
rs7303997412:5547187A/CNTF3intron0.9630.961750.01800.03025
rs7303997912:5548661T/GNTF3intron0.8910.985700.01530.34422b
rs7303998412:5549456T/CNTF3intron0.9771.037800.01790.037796
rs731479412:5569271T/CNTF3intron0.9931.003000.01080.78316
rs7325935312:5588129T/CNTF3intron0.9461.058130.02630.03147
rs7405633712:5544331T/CNTF3intron0.9510.960690.01810.02685
rs7405636512:5578484T/CNTF3intron0.9760.971510.05420.5946
rs7405636612:5578839A/GNTF3intron0.9760.971510.05420.59396
rs7474279312:5562344A/GNTF3intron0.9770.988370.01520.44316
rs7476866312:5622824T/CNTF3intron0.9520.972390.02100.18226
rs748440112:5599902C/GNTF3intron0.9890.986990.01070.21987
rs7579100212:5548441T/CNTF3intron0.7751.005010.03500.88714
rs7591487912:5562283T/CNTF3intron0.9681.006420.01860.73037
rs7592851112:5594988A/CNTF3intron0.8021.001700.03870.96585
rs7593043812:5583574A/GNTF3intron0.8170.950180.03400.13267
rs7616877812:5549716A/GNTF3intron0.8500.966570.03430.32095
rs7646668612:5594263T/GNTF3intron0.6301.124910.05680.038156
rs7672731912:5553031A/GNTF3intron0.7950.982260.02900.53776
rs7692125712:5577950C/GNTF3intron0.9381.047280.04330.28667
rs7698273012:5548171A/TNTF3intron0.9431.006920.02460.77855
rs7720877812:5573935T/CNTF3intron0.9041.006320.05410.90757
rs7742416812:5562122A/GNTF3intron0.9680.989160.01910.56825
rs7809504212:5598795A/CNTF3intron0.8721.026550.02960.37617
rs7901206412:5628657A/GNTF3intron0.8741.016940.02900.56175
rs7901312912:5589272C/GNTF3intron0.9600.987970.01850.51485
rs7921155812:5596571T/GNTF3intron0.7380.952180.05600.38177
rs7929672912:5629790A/TNTF3intron0.9811.020000.02040.33187
rs7973096412:5596781T/CNTF3intron0.9041.108270.04710.029047
rs7983299312:5560021A/GNTF3intron0.9000.992130.01140.49136
rs8007036112:5589893C/GNTF3intron0.9580.988270.01860.52445
rs8022454112:5560979T/CNTF3intron0.8450.956570.03270.17367
rs91817712:5553061A/GNTF3intron0.9560.965900.01110.0017977
rs988833812:5548301T/CNTF3intron0.9550.975210.01330.059424
SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*

  Note: RegulomeDB score*
score supporting data score supporting data
1aeQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak6other
2aTF binding + matched TF motif + matched DNase Footprint + DNase peak5TF binding or DNase peak
1beQTL + TF binding + any motif + DNase Footprint + DNase peak4TF binding + DNase peak
2bTF binding + any motif + DNase Footprint + DNase peak3bTF binding + matched TF motif
1ceQTL + TF binding + matched TF motif + DNase peak1feQTL + TF binding / DNase peak
2cTF binding + matched TF motif + DNase peak3aTF binding + any motif + DNase peak
1deQTL + TF binding + any motif + DNase peak1eeQTL + TF binding + matched TF motif
CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation
KEGG pathway annotationhsa04010; MAPK signaling pathway
KEGG pathway annotationhsa04722; Neurotrophin signaling pathway
GO annotation
GO pathway annotationGO:0000187; activation of MAPK activity
GO pathway annotationGO:0002092; positive regulation of receptor internalization
GO pathway annotationGO:0005102; receptor binding
GO pathway annotationGO:0005166; neurotrophin p75 receptor binding
GO pathway annotationGO:0005515; protein binding
GO pathway annotationGO:0005576; extracellular region
GO pathway annotationGO:0007165; signal transduction
GO pathway annotationGO:0007169; transmembrane receptor protein tyrosine kinase signaling pathway
GO pathway annotationGO:0007267; cell-cell signaling
GO pathway annotationGO:0007274; neuromuscular synaptic transmission
GO pathway annotationGO:0007399; nervous system development
GO pathway annotationGO:0007403; glial cell fate determination
GO pathway annotationGO:0007411; axon guidance
GO pathway annotationGO:0007420; brain development
GO pathway annotationGO:0007422; peripheral nervous system development
GO pathway annotationGO:0008083; growth factor activity
GO pathway annotationGO:0008284; positive regulation of cell proliferation
GO pathway annotationGO:0008544; epidermis development
GO pathway annotationGO:0016023; cytoplasmic membrane-bounded vesicle
GO pathway annotationGO:0021675; nerve development
GO pathway annotationGO:0030335; positive regulation of cell migration
GO pathway annotationGO:0032148; activation of protein kinase B activity
GO pathway annotationGO:0033138; positive regulation of peptidyl-serine phosphorylation
GO pathway annotationGO:0042056; chemoattractant activity
GO pathway annotationGO:0042490; mechanoreceptor differentiation
GO pathway annotationGO:0042552; myelination
GO pathway annotationGO:0042981; regulation of apoptotic process
GO pathway annotationGO:0043524; negative regulation of neuron apoptotic process
GO pathway annotationGO:0045664; regulation of neuron differentiation
GO pathway annotationGO:0045687; positive regulation of glial cell differentiation
GO pathway annotationGO:0045944; positive regulation of transcription from RNA polymerase II promoter
GO pathway annotationGO:0048406; nerve growth factor binding
GO pathway annotationGO:0048484; enteric nervous system development
GO pathway annotationGO:0048812; neuron projection morphogenesis
GO pathway annotationGO:0050731; positive regulation of peptidyl-tyrosine phosphorylation
GO pathway annotationGO:0050732; negative regulation of peptidyl-tyrosine phosphorylation
GO pathway annotationGO:0050804; modulation of synaptic transmission
GO pathway annotationGO:0050918; positive chemotaxis
GO pathway annotationGO:0050930; induction of positive chemotaxis
GO pathway annotationGO:0051145; smooth muscle cell differentiation
GO pathway annotationGO:0090630; activation of GTPase activity
GO pathway annotationGO:2000251; positive regulation of actin cytoskeleton reorganization
Co-expression Information

There is no gene co-express this gene!

Expression pattern
Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction