ITIH1

Basic Information
Gene SymbolITIH1
Entrez Id3697
Positionchr3:52811608..52826077
Descriptioninter-alpha-trypsin inhibitor heavy chain 1
Gene typeprotein-coding
SNP Information

SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*
rs10756533:52825528T/CITIH1intron0.9941.057920.01102.991E-71f
rs10764253:52825462A/GITIH1intron0.9941.058760.01101.987E-71f
rs1114779143:52821666T/CITIH1intron0.7431.015420.04900.75465
rs131008263:52810845T/CITIH1near-gene-50.7490.963770.02500.13896
rs1388804913:52813701C/GITIH1intron,near-gene-50.7221.027370.03300.4129-
rs1452252923:52818986T/CITIH1intron0.7501.099440.05430.08078-
rs1459190953:52819416A/GITIH1intron0.7111.100980.05920.1042-
rs20715063:52826276T/CITIH1near-gene-30.9941.056960.01104.622E-71f
rs20981673:52810933A/TITIH1near-gene-50.9191.055590.01152.424E-66
rs22395493:52823126A/GITIH1intron0.9950.944970.01091.877E-71f
rs22395503:52822509C/GITIH1intron0.9930.945820.01092.931E-75
rs22395513:52818579A/GITIH1intron0.9930.945920.01093.125E-76
rs22680233:52819327A/TITIH1intron0.9660.949610.01092.135E-65
rs22701973:52824095T/GITIH1intron0.9941.059400.01101.569E-71f
rs22843503:52822856T/CITIH1intron0.9751.057070.01104.466E-76
rs22843513:52822789T/CITIH1intron0.9211.052430.01158.565E-67
rs22867983:52821177A/CITIH1intron0.9911.058870.01101.773E-71f
rs23001493:52822921T/CITIH1intron0.9950.945820.01092.8E-76
rs23024173:52814256A/TITIH1intron0.9710.935480.01074.471E-106
rs25356303:52819883T/GITIH1intron0.6621.083830.04450.070796
rs27103223:52817593T/CITIH1intron0.9611.015110.01590.34465
rs27103233:52815905T/CITIH1intron0.9871.071220.01069.124E-111f
rs360120323:52814709A/CITIH1intron0.9670.952180.01960.012257
rs46875513:52823448T/CITIH1intron0.9901.058230.01102.66E-71f
rs622554003:52812231T/CITIH1intron,near-gene-50.9360.975020.01870.17754
rs67783293:52824610A/GITIH1intron0.9940.945630.01103.667E-71f
rs6783:52820981A/TITIH1missense0.9931.059080.01101.613E-71f
rs750977603:52814643T/CITIH1intron0.8940.993120.04230.86997
rs762030173:52814255A/TITIH1intron0.9390.982360.01910.35036
SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*

  Note: RegulomeDB score*
score supporting data score supporting data
1aeQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak6other
2aTF binding + matched TF motif + matched DNase Footprint + DNase peak5TF binding or DNase peak
1beQTL + TF binding + any motif + DNase Footprint + DNase peak4TF binding + DNase peak
2bTF binding + any motif + DNase Footprint + DNase peak3bTF binding + matched TF motif
1ceQTL + TF binding + matched TF motif + DNase peak1feQTL + TF binding / DNase peak
2cTF binding + matched TF motif + DNase peak3aTF binding + any motif + DNase peak
1deQTL + TF binding + any motif + DNase peak1eeQTL + TF binding + matched TF motif
CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation

There is no pathway information about this gene!

GO annotation
GO pathway annotationGO:0004867; serine-type endopeptidase inhibitor activity
GO pathway annotationGO:0005509; calcium ion binding
GO pathway annotationGO:0005576; extracellular region
GO pathway annotationGO:0010951; negative regulation of endopeptidase activity
GO pathway annotationGO:0030212; hyaluronan metabolic process
GO pathway annotationGO:0070062; extracellular exosome
GO pathway annotationGO:0072562; blood microparticle
Co-expression Information

There is no gene co-express this gene!

Expression pattern
Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction