IL3

Basic Information
Gene SymbolIL3
Entrez Id3562
Positionchr5:131396347..131398896
Descriptioninterleukin 3
Gene typeprotein-coding
SNP Information

SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*
rs20735065:131394738T/CIL3near-gene-50.9991.004110.01770.81715
rs761671685:131394455A/CIL3near-gene-50.9800.962710.02270.094385
SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*

  Note: RegulomeDB score*
score supporting data score supporting data
1aeQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak6other
2aTF binding + matched TF motif + matched DNase Footprint + DNase peak5TF binding or DNase peak
1beQTL + TF binding + any motif + DNase Footprint + DNase peak4TF binding + DNase peak
2bTF binding + any motif + DNase Footprint + DNase peak3bTF binding + matched TF motif
1ceQTL + TF binding + matched TF motif + DNase peak1feQTL + TF binding / DNase peak
2cTF binding + matched TF motif + DNase peak3aTF binding + any motif + DNase peak
1deQTL + TF binding + any motif + DNase peak1eeQTL + TF binding + matched TF motif
CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation
KEGG pathway annotationhsa04060; Cytokine-cytokine receptor interaction
KEGG pathway annotationhsa04151; PI3K-Akt signaling pathway
KEGG pathway annotationhsa04210; Apoptosis
KEGG pathway annotationhsa04630; Jak-STAT signaling pathway
KEGG pathway annotationhsa04640; Hematopoietic cell lineage
KEGG pathway annotationhsa04664; Fc epsilon RI signaling pathway
KEGG pathway annotationhsa05202; Transcriptional misregulation in cancer
KEGG pathway annotationhsa05310; Asthma
GO annotation
GO pathway annotationGO:0000165; MAPK cascade
GO pathway annotationGO:0000186; activation of MAPKK activity
GO pathway annotationGO:0002763; positive regulation of myeloid leukocyte differentiation
GO pathway annotationGO:0005125; cytokine activity
GO pathway annotationGO:0005135; interleukin-3 receptor binding
GO pathway annotationGO:0005576; extracellular region
GO pathway annotationGO:0005615; extracellular space
GO pathway annotationGO:0005622; intracellular
GO pathway annotationGO:0007173; epidermal growth factor receptor signaling pathway
GO pathway annotationGO:0007264; small GTPase mediated signal transduction
GO pathway annotationGO:0007265; Ras protein signal transduction
GO pathway annotationGO:0007267; cell-cell signaling
GO pathway annotationGO:0007399; nervous system development
GO pathway annotationGO:0007411; axon guidance
GO pathway annotationGO:0008083; growth factor activity
GO pathway annotationGO:0008284; positive regulation of cell proliferation
GO pathway annotationGO:0008286; insulin receptor signaling pathway
GO pathway annotationGO:0008543; fibroblast growth factor receptor signaling pathway
GO pathway annotationGO:0019221; cytokine-mediated signaling pathway
GO pathway annotationGO:0035162; embryonic hemopoiesis
GO pathway annotationGO:0038095; Fc-epsilon receptor signaling pathway
GO pathway annotationGO:0042523; positive regulation of tyrosine phosphorylation of Stat5 protein
GO pathway annotationGO:0045087; innate immune response
GO pathway annotationGO:0045740; positive regulation of DNA replication
GO pathway annotationGO:0048010; vascular endothelial growth factor receptor signaling pathway
GO pathway annotationGO:0048011; neurotrophin TRK receptor signaling pathway
GO pathway annotationGO:0050731; positive regulation of peptidyl-tyrosine phosphorylation
GO pathway annotationGO:0070668; positive regulation of mast cell proliferation
Co-expression Information

There is no gene co-express this gene!

Expression pattern
Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction