HSPA1B

Basic Information
Gene SymbolHSPA1B
Entrez Id3304
Positionchr6:3305094..3307616
Descriptionheat shock 70kDa protein 1B
Gene typeprotein-coding
SNP Information

SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*
rs1483103766:31794419A/GHSPA1Bnear-gene-50.8981.046660.05760.4281-
rs1890050166:31798454A/GHSPA1Bnear-gene-30.9431.011570.03850.7658-
SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*

  Note: RegulomeDB score*
score supporting data score supporting data
1aeQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak6other
2aTF binding + matched TF motif + matched DNase Footprint + DNase peak5TF binding or DNase peak
1beQTL + TF binding + any motif + DNase Footprint + DNase peak4TF binding + DNase peak
2bTF binding + any motif + DNase Footprint + DNase peak3bTF binding + matched TF motif
1ceQTL + TF binding + matched TF motif + DNase peak1feQTL + TF binding / DNase peak
2cTF binding + matched TF motif + DNase peak3aTF binding + any motif + DNase peak
1deQTL + TF binding + any motif + DNase peak1eeQTL + TF binding + matched TF motif
CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation
KEGG pathway annotationhsa03040; Spliceosome
KEGG pathway annotationhsa04010; MAPK signaling pathway
KEGG pathway annotationhsa04141; Protein processing in endoplasmic reticulum
KEGG pathway annotationhsa04144; Endocytosis
KEGG pathway annotationhsa04612; Antigen processing and presentation
KEGG pathway annotationhsa04915; Estrogen signaling pathway
KEGG pathway annotationhsa05134; Legionellosis
KEGG pathway annotationhsa05145; Toxoplasmosis
KEGG pathway annotationhsa05162; Measles
KEGG pathway annotationhsa05164; Influenza A
KEGG pathway annotationhsa05169; Epstein-Barr virus infection
GO annotation
GO pathway annotationGO:0000151; ubiquitin ligase complex
GO pathway annotationGO:0001618; virus receptor activity
GO pathway annotationGO:0001664; G-protein coupled receptor binding
GO pathway annotationGO:0005102; receptor binding
GO pathway annotationGO:0005515; protein binding
GO pathway annotationGO:0005524; ATP binding
GO pathway annotationGO:0005654; nucleoplasm
GO pathway annotationGO:0005737; cytoplasm
GO pathway annotationGO:0005814; centriole
GO pathway annotationGO:0005829; cytosol
GO pathway annotationGO:0005925; focal adhesion
GO pathway annotationGO:0010628; positive regulation of gene expression
GO pathway annotationGO:0010941; regulation of cell death
GO pathway annotationGO:0016234; inclusion body
GO pathway annotationGO:0016887; ATPase activity
GO pathway annotationGO:0019899; enzyme binding
GO pathway annotationGO:0031072; heat shock protein binding
GO pathway annotationGO:0031396; regulation of protein ubiquitination
GO pathway annotationGO:0031397; negative regulation of protein ubiquitination
GO pathway annotationGO:0031625; ubiquitin protein ligase binding
GO pathway annotationGO:0032757; positive regulation of interleukin-8 production
GO pathway annotationGO:0034599; cellular response to oxidative stress
GO pathway annotationGO:0034605; cellular response to heat
GO pathway annotationGO:0042026; protein refolding
GO pathway annotationGO:0042623; ATPase activity, coupled
GO pathway annotationGO:0042826; histone deacetylase binding
GO pathway annotationGO:0044183; protein binding involved in protein folding
GO pathway annotationGO:0046034; ATP metabolic process
GO pathway annotationGO:0046718; viral entry into host cell
GO pathway annotationGO:0048471; perinuclear region of cytoplasm
GO pathway annotationGO:0050821; protein stabilization
GO pathway annotationGO:0051082; unfolded protein binding
GO pathway annotationGO:0051092; positive regulation of NF-kappaB transcription factor activity
GO pathway annotationGO:0055131; C3HC4-type RING finger domain binding
GO pathway annotationGO:0060548; negative regulation of cell death
GO pathway annotationGO:0070370; cellular heat acclimation
GO pathway annotationGO:0070434; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
GO pathway annotationGO:0072562; blood microparticle
GO pathway annotationGO:0090084; negative regulation of inclusion body assembly
GO pathway annotationGO:1900034; regulation of cellular response to heat
GO pathway annotationGO:1903265; positive regulation of tumor necrosis factor-mediated signaling pathway
GO pathway annotationGO:2001240; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Co-expression Information

There is no gene co-express this gene!

Expression pattern
Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction