GABRA6

Basic Information
Gene SymbolGABRA6
Entrez Id2559
Positionchr5:161112658..161129598
Descriptiongamma-aminobutyric acid (GABA) A receptor, alpha 6
Gene typeprotein-coding
SNP Information

SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*
rs1172343575:161121147A/GGABRA6intron0.9851.010860.03800.7767
rs119491585:161127234A/GGABRA6intron1.0001.011670.01300.37426
rs119567315:161127822T/CGABRA6intron1.0101.012980.01320.32826
rs119592285:161127111A/GGABRA6intron0.9940.960210.01390.0034997
rs131659445:161120538T/CGABRA6intron1.0000.998400.01210.89476
rs131719545:161120411A/CGABRA6intron1.0100.988170.01060.26246
rs131729145:161124464T/CGABRA6intron1.0000.986690.01060.2087
rs131845865:161119125C/GGABRA6coding-synon1.0100.988170.01060.26187
rs131889915:161113004A/GGABRA6coding-synon0.9651.021120.01230.089527
rs131900345:161120821T/CGABRA6intron1.0000.983730.01100.13516
rs1446777225:161111858T/GGABRA6near-gene-50.8140.928110.06610.259-
rs174654865:161127876T/CGABRA6intron0.9861.018880.04030.64297
rs1863476635:161127271A/GGABRA6intron0.8530.999200.04120.984-
rs1868917955:161112020C/GGABRA6near-gene-50.7810.959250.05530.4526-
rs19926465:161111261A/CGABRA6near-gene-51.0000.987870.01060.24917
rs19926475:161111174A/GGABRA6near-gene-50.9991.017650.01090.10987
rs32191515:161128914T/CGABRA6untranslated-31.0001.012170.01060.25677
rs349078045:161128627T/CGABRA6missense0.9951.014910.02100.48226
rs38119915:161128409A/CGABRA6intron1.0000.983140.01100.12156
rs38119925:161116942A/GGABRA6intron1.0100.987680.01060.24357
rs38119935:161116672T/CGABRA6missense0.7940.954370.05400.3877
rs38119955:161112693T/CGABRA6untranslated-51.0001.011770.01060.26997
rs412753155:161113492A/TGABRA6intron1.0101.011870.01310.37066
rs413116315:161117041T/CGABRA6intron1.0001.016130.02120.44916
rs49211955:161111588T/CGABRA6near-gene-50.9971.041640.01390.0034387
rs623816305:161126670A/GGABRA6intron1.0000.987780.01060.24887
rs65565585:161125325T/CGABRA6intron1.0000.983640.01100.1327
rs65565595:161125546T/GGABRA6intron1.0001.012070.01060.25696
rs68650425:161129836A/GGABRA6near-gene-31.0000.983640.01100.13187
rs68796185:161121999T/CGABRA6intron0.9951.016330.01160.1617
rs68837585:161130045C/GGABRA6near-gene-30.9971.041230.01390.0036817
rs68838295:161122848C/GGABRA6intron1.0001.016640.01100.13276
rs68985715:161128019T/CGABRA6intron0.9970.984320.01150.17217
rs728155265:160976104T/GGABRA6near-gene-50.9790.989160.01160.34835
rs728174225:161126271T/CGABRA6intron0.9970.960410.01390.0037457
rs733075655:161119877T/GGABRA6intron1.0001.014710.02100.48537
rs733075765:161120835T/CGABRA6intron0.9790.986290.02090.50866
rs752131955:161112050A/TGABRA6near-gene-50.6141.038520.03900.3337
rs758443055:161123009A/TGABRA6intron0.8351.054850.04740.26017
rs760608005:161123507A/GGABRA6intron0.9971.015210.02120.47616
rs772435575:161123013A/CGABRA6intron1.0101.010150.01320.4477
rs798027865:161118630A/GGABRA6intron0.9421.002300.03300.9446
rs800448145:161123787T/CGABRA6intron0.9971.015210.02120.47637
rs93138925:161110992A/GGABRA6near-gene-50.9970.960020.01390.0034337
rs96881985:161127749A/GGABRA6intron1.0100.986990.01320.31987
SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*

  Note: RegulomeDB score*
score supporting data score supporting data
1aeQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak6other
2aTF binding + matched TF motif + matched DNase Footprint + DNase peak5TF binding or DNase peak
1beQTL + TF binding + any motif + DNase Footprint + DNase peak4TF binding + DNase peak
2bTF binding + any motif + DNase Footprint + DNase peak3bTF binding + matched TF motif
1ceQTL + TF binding + matched TF motif + DNase peak1feQTL + TF binding / DNase peak
2cTF binding + matched TF motif + DNase peak3aTF binding + any motif + DNase peak
1deQTL + TF binding + any motif + DNase peak1eeQTL + TF binding + matched TF motif
CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation
KEGG pathway annotationhsa04080; Neuroactive ligand-receptor interaction
KEGG pathway annotationhsa04723; Retrograde endocannabinoid signaling
KEGG pathway annotationhsa04727; GABAergic synapse
KEGG pathway annotationhsa05032; Morphine addiction
KEGG pathway annotationhsa05033; Nicotine addiction
GO annotation
GO pathway annotationGO:0004890; GABA-A receptor activity
GO pathway annotationGO:0005230; extracellular ligand-gated ion channel activity
GO pathway annotationGO:0005254; chloride channel activity
GO pathway annotationGO:0005886; plasma membrane
GO pathway annotationGO:0005887; integral component of plasma membrane
GO pathway annotationGO:0006810; transport
GO pathway annotationGO:0007165; signal transduction
GO pathway annotationGO:0007214; gamma-aminobutyric acid signaling pathway
GO pathway annotationGO:0007268; synaptic transmission
GO pathway annotationGO:0008503; benzodiazepine receptor activity
GO pathway annotationGO:0030054; cell junction
GO pathway annotationGO:0034220; ion transmembrane transport
GO pathway annotationGO:0034707; chloride channel complex
GO pathway annotationGO:0045211; postsynaptic membrane
GO pathway annotationGO:0055085; transmembrane transport
GO pathway annotationGO:1902476; chloride transmembrane transport
GO pathway annotationGO:1902711; GABA-A receptor complex
Co-expression Information

There is no gene co-express this gene!

Expression pattern
Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction