FAS

Basic Information
Gene SymbolFAS
Entrez Id355
Positionchr10:90750288..90775542
DescriptionFas cell surface death receptor
Gene typeprotein-coding
SNP Information

SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*
rs105107010:90774772A/TFASncRNA,untranslated-30.9200.982950.01810.3426
rs1088787710:90753038A/GFASintron,near-gene-50.9960.987580.01050.23482b
rs11208173010:90753273T/CFASintron,near-gene-50.8601.005110.02000.79754
rs11757878810:90756937T/CFASintron0.8190.981960.04970.71394
rs1235936210:90753145C/GFASintron,near-gene-50.9930.988960.01090.31044
rs1272043510:90768018A/GFASintron0.9740.994810.02670.84447
rs1272043610:90768825A/GFASintron0.8051.052850.05230.32477
rs157101110:90757787A/CFASintron0.9851.001700.01070.87256
rs157101310:90758349A/GFASintron0.9851.001200.01080.91416
rs157101910:90773303A/GFASintron0.9890.999300.01060.94937
rs157102010:90770852T/CFASintron0.9941.004810.01190.68627
rs18585753710:90759257T/CFASintron0.7721.077560.05940.2086-
rs18620523310:90758802T/CFASintron0.8981.026340.04260.542-
rs197738910:90773494T/GFASintron0.9921.000700.01080.94716
rs203161010:90754487T/CFASintron,near-gene-50.9921.011160.01090.31067
rs203161110:90767395C/GFASintron0.9911.005310.01190.65497
rs203161210:90766980T/CFASintron0.9891.001000.01080.92957
rs203161310:90766924T/CFASintron0.9921.005520.01190.64577
rs214741810:90760000T/CFASintron0.9790.978240.01620.17556
rs214741910:90759916T/GFASintron0.9821.003810.01210.75377
rs214742010:90759613A/GFASintron0.9851.006720.01070.53331b
rs214828610:90759924A/GFASintron0.9850.998100.01080.85957
rs214828710:90759772T/CFASintron0.9830.993220.01070.52625
rs218240810:90760107T/CFASintron0.9841.007130.01070.50637
rs222952110:90767482A/GFAScoding-synon,intron,ncRNA0.9740.994710.02670.84417
rs223497810:90771829T/CFAScoding-synon,ncRNA0.9930.995610.01190.71116
rs229660010:90770439C/GFASintron0.9921.000500.01080.95946
rs229660110:90767640T/CFASintron0.9991.023270.01630.15886
rs229660210:90767347T/CFASintron0.9981.022860.01630.16586
rs229660310:90763127T/CFASintron0.9840.998100.01080.85814
rs229660410:90761715A/GFASintron0.9870.979120.01610.18795
rs321861310:90762938A/GFAScoding-synon,ncRNA0.9120.960980.05270.45097
rs321862010:90770373T/CFASintron0.8031.058130.05310.28696
rs378120210:90769464A/GFASintron0.9920.999500.01080.96216
rs378120410:90752343T/CFASintron,near-gene-5,ncRNA0.9751.018980.01610.24355
rs382472910:90752616A/GFASintron,near-gene-5,ncRNA0.9960.987580.01050.23465
rs434587810:90756511T/CFASintron0.9530.996010.01600.80046
rs440673710:90759724A/GFASintron0.9851.007130.01070.50841d
rs440673810:90760012A/TFASintron0.9851.006920.01070.51546
rs658616510:90755056A/TFASintron0.9911.012380.01060.24381f
rs658616610:90756065T/CFASintron0.9811.012070.01060.25946
rs658616710:90756146T/GFASintron0.9800.988170.01060.26426
rs706906110:90754909A/GFASintron0.9920.986890.01060.21095
rs706975010:90762376T/GFASintron0.9850.993120.01070.51875
rs707282810:90754953T/GFASintron0.9900.987870.01060.24975
rs707619710:90753134T/CFASintron,near-gene-50.9891.018160.01610.26432a
rs789678910:90764864T/CFASintron0.9820.980790.01610.22817
rs932560310:90754155C/GFASintron,near-gene-50.9801.018370.01630.26331f
rs965868510:90755400T/CFASintron0.9751.017650.01640.28345
rs965869110:90756163T/CFASintron0.9611.010960.01670.51466
rs965869610:90756576A/GFASintron0.7851.086760.04690.076315
rs965869910:90756694A/GFASintron0.9051.011870.03140.70714
rs965870210:90757245A/GFASintron0.9651.048540.02390.047366
rs965870610:90757620A/GFASintron0.9380.979900.01840.2691f
rs965871310:90759156C/GFASintron0.9651.001100.02900.97036
rs965872710:90761865T/CFASintron0.9711.010250.01540.50845
rs965874110:90764739A/GFASintron0.9761.003100.01080.77457
rs965874210:90764891C/GFASintron0.9720.996010.01070.70746
rs965874810:90765647T/GFASintron0.9041.020410.01800.26227
rs965875010:90766596A/GFASintron0.9821.011970.01480.42297
rs965875710:90769455T/CFASintron0.9871.010960.01480.4626
rs965876110:90769886T/GFASintron0.9230.979610.01800.2526
rs965876510:90771505A/GFASintron0.9770.994220.02670.82647
rs965876610:90771612A/GFASintron0.9870.989260.01480.46387
rs965876710:90772272T/GFASintron1.0001.023570.01630.15327
rs965876910:90773363A/CFASintron1.0001.023570.01630.15296
rs965877010:90773421C/GFASintron0.9761.005010.02670.85047
rs965877110:90773525A/GFASintron0.7120.934630.04110.10046
rs965877610:90774972T/CFASncRNA,untranslated-30.9760.995010.02670.85047
rs98276410:90769998T/CFASintron0.9910.994810.01140.64747
SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*

  Note: RegulomeDB score*
score supporting data score supporting data
1aeQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak6other
2aTF binding + matched TF motif + matched DNase Footprint + DNase peak5TF binding or DNase peak
1beQTL + TF binding + any motif + DNase Footprint + DNase peak4TF binding + DNase peak
2bTF binding + any motif + DNase Footprint + DNase peak3bTF binding + matched TF motif
1ceQTL + TF binding + matched TF motif + DNase peak1feQTL + TF binding / DNase peak
2cTF binding + matched TF motif + DNase peak3aTF binding + any motif + DNase peak
1deQTL + TF binding + any motif + DNase peak1eeQTL + TF binding + matched TF motif
CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation
KEGG pathway annotationhsa04010; MAPK signaling pathway
KEGG pathway annotationhsa04060; Cytokine-cytokine receptor interaction
KEGG pathway annotationhsa04115; p53 signaling pathway
KEGG pathway annotationhsa04210; Apoptosis
KEGG pathway annotationhsa04650; Natural killer cell mediated cytotoxicity
KEGG pathway annotationhsa04668; TNF signaling pathway
KEGG pathway annotationhsa04932; Non-alcoholic fatty liver disease (NAFLD)
KEGG pathway annotationhsa04940; Type I diabetes mellitus
KEGG pathway annotationhsa05010; Alzheimer's disease
KEGG pathway annotationhsa05142; Chagas disease (American trypanosomiasis)
KEGG pathway annotationhsa05143; African trypanosomiasis
KEGG pathway annotationhsa05161; Hepatitis B
KEGG pathway annotationhsa05162; Measles
KEGG pathway annotationhsa05164; Influenza A
KEGG pathway annotationhsa05168; Herpes simplex infection
KEGG pathway annotationhsa05200; Pathways in cancer
KEGG pathway annotationhsa05205; Proteoglycans in cancer
KEGG pathway annotationhsa05320; Autoimmune thyroid disease
KEGG pathway annotationhsa05330; Allograft rejection
KEGG pathway annotationhsa05332; Graft-versus-host disease
GO annotation
GO pathway annotationGO:0001552; ovarian follicle atresia
GO pathway annotationGO:0002020; protease binding
GO pathway annotationGO:0002377; immunoglobulin production
GO pathway annotationGO:0003014; renal system process
GO pathway annotationGO:0004871; signal transducer activity
GO pathway annotationGO:0004872; receptor activity
GO pathway annotationGO:0005031; tumor necrosis factor-activated receptor activity
GO pathway annotationGO:0005515; protein binding
GO pathway annotationGO:0005615; extracellular space
GO pathway annotationGO:0005634; nucleus
GO pathway annotationGO:0005737; cytoplasm
GO pathway annotationGO:0005829; cytosol
GO pathway annotationGO:0005886; plasma membrane
GO pathway annotationGO:0005887; integral component of plasma membrane
GO pathway annotationGO:0006461; protein complex assembly
GO pathway annotationGO:0006915; apoptotic process
GO pathway annotationGO:0006919; activation of cysteine-type endopeptidase activity involved in apoptotic process
GO pathway annotationGO:0006924; activation-induced cell death of T cells
GO pathway annotationGO:0006925; inflammatory cell apoptotic process
GO pathway annotationGO:0006927; transformed cell apoptotic process
GO pathway annotationGO:0006954; inflammatory response
GO pathway annotationGO:0006955; immune response
GO pathway annotationGO:0007165; signal transduction
GO pathway annotationGO:0007166; cell surface receptor signaling pathway
GO pathway annotationGO:0007283; spermatogenesis
GO pathway annotationGO:0007420; brain development
GO pathway annotationGO:0007568; aging
GO pathway annotationGO:0007623; circadian rhythm
GO pathway annotationGO:0008625; extrinsic apoptotic signaling pathway via death domain receptors
GO pathway annotationGO:0009636; response to toxic substance
GO pathway annotationGO:0009897; external side of plasma membrane
GO pathway annotationGO:0009986; cell surface
GO pathway annotationGO:0010468; regulation of gene expression
GO pathway annotationGO:0010939; regulation of necrotic cell death
GO pathway annotationGO:0012501; programmed cell death
GO pathway annotationGO:0016324; apical plasma membrane
GO pathway annotationGO:0019724; B cell mediated immunity
GO pathway annotationGO:0019900; kinase binding
GO pathway annotationGO:0021537; telencephalon development
GO pathway annotationGO:0030141; secretory granule
GO pathway annotationGO:0031104; dendrite regeneration
GO pathway annotationGO:0031264; death-inducing signaling complex
GO pathway annotationGO:0031265; CD95 death-inducing signaling complex
GO pathway annotationGO:0032403; protein complex binding
GO pathway annotationGO:0032464; positive regulation of protein homooligomerization
GO pathway annotationGO:0032496; response to lipopolysaccharide
GO pathway annotationGO:0033209; tumor necrosis factor-mediated signaling pathway
GO pathway annotationGO:0042127; regulation of cell proliferation
GO pathway annotationGO:0042383; sarcolemma
GO pathway annotationGO:0042493; response to drug
GO pathway annotationGO:0042698; ovulation cycle
GO pathway annotationGO:0042802; identical protein binding
GO pathway annotationGO:0042981; regulation of apoptotic process
GO pathway annotationGO:0043005; neuron projection
GO pathway annotationGO:0043009; chordate embryonic development
GO pathway annotationGO:0043025; neuronal cell body
GO pathway annotationGO:0043065; positive regulation of apoptotic process
GO pathway annotationGO:0043066; negative regulation of apoptotic process
GO pathway annotationGO:0043154; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO pathway annotationGO:0043281; regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO pathway annotationGO:0043410; positive regulation of MAPK cascade
GO pathway annotationGO:0043434; response to peptide hormone
GO pathway annotationGO:0045060; negative thymic T cell selection
GO pathway annotationGO:0045121; membrane raft
GO pathway annotationGO:0045619; regulation of lymphocyte differentiation
GO pathway annotationGO:0045637; regulation of myeloid cell differentiation
GO pathway annotationGO:0046898; response to cycloheximide
GO pathway annotationGO:0048471; perinuclear region of cytoplasm
GO pathway annotationGO:0048536; spleen development
GO pathway annotationGO:0050869; negative regulation of B cell activation
GO pathway annotationGO:0051260; protein homooligomerization
GO pathway annotationGO:0051384; response to glucocorticoid
GO pathway annotationGO:0060135; maternal process involved in female pregnancy
GO pathway annotationGO:0070062; extracellular exosome
GO pathway annotationGO:0070266; necroptotic process
GO pathway annotationGO:0070301; cellular response to hydrogen peroxide
GO pathway annotationGO:0070848; response to growth factor
GO pathway annotationGO:0071234; cellular response to phenylalanine
GO pathway annotationGO:0071260; cellular response to mechanical stimulus
GO pathway annotationGO:0071279; cellular response to cobalt ion
GO pathway annotationGO:0071285; cellular response to lithium ion
GO pathway annotationGO:0071333; cellular response to glucose stimulus
GO pathway annotationGO:0071347; cellular response to interleukin-1
GO pathway annotationGO:0071391; cellular response to estrogen stimulus
GO pathway annotationGO:0071455; cellular response to hyperoxia
GO pathway annotationGO:0071456; cellular response to hypoxia
GO pathway annotationGO:0071464; cellular response to hydrostatic pressure
GO pathway annotationGO:0097049; motor neuron apoptotic process
GO pathway annotationGO:0097190; apoptotic signaling pathway
GO pathway annotationGO:0097191; extrinsic apoptotic signaling pathway
GO pathway annotationGO:0097192; extrinsic apoptotic signaling pathway in absence of ligand
GO pathway annotationGO:0097284; hepatocyte apoptotic process
GO pathway annotationGO:0097296; activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO pathway annotationGO:0097300; programmed necrotic cell death
GO pathway annotationGO:0097421; liver regeneration
GO pathway annotationGO:0097440; apical dendrite
GO pathway annotationGO:0097527; necroptotic signaling pathway
GO pathway annotationGO:1902041; regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO pathway annotationGO:1902617; response to fluoride
GO pathway annotationGO:2001241; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
Co-expression Information

There is no gene co-express this gene!

Expression pattern

There is no expression information about these genes!

Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction