ERCC4

Basic Information
Gene SymbolERCC4
Entrez Id2072
Positionchr16:14014014..14046205
Descriptionexcision repair cross-complementation group 4
Gene typeprotein-coding
SNP Information

SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*
rs1107522316:14044717A/CERCC4ncRNA,untranslated-30.9961.017350.01120.12527
rs11225969216:14046117C/GERCC4ncRNA,untranslated-30.9791.016130.02380.50097
rs11340363316:14046005T/CERCC4ncRNA,untranslated-30.9591.013900.02360.55956
rs1164466616:14046472A/GERCC4near-gene-30.9930.985700.01180.21947
rs11729322616:14043151T/CERCC4ncRNA,untranslated-30.7600.932860.06590.2915
rs1696325516:14042108A/GERCC4coding-synon,ncRNA0.8351.093740.04650.05425
rs179979716:14013993A/TERCC4near-gene-50.9851.010350.01190.38324
rs179979816:14014278A/GERCC4intron0.7920.968890.02010.11524
rs179979916:14038545T/CERCC4intron0.9980.982750.01120.11936
rs179980016:14038552A/GERCC4intron0.9941.011360.01180.34147
rs179980116:14041958T/CERCC4coding-synon,ncRNA0.9950.986890.01170.25986
rs180012416:14042077A/GERCC4ncRNA,missense0.9280.974630.04310.55015
rs223846216:14015310C/GERCC4intron0.9840.990050.01190.39945
rs223846316:14017902C/GERCC4intron0.9850.982850.01120.12213a
rs227646416:14042930C/GERCC4ncRNA,untranslated-30.9951.011970.01170.30787
rs227646516:14043014A/GERCC4ncRNA,untranslated-30.9961.017760.01120.11557
rs227646616:14043175C/GERCC4ncRNA,untranslated-30.9950.987970.01170.30025
rs313603816:14013379T/CERCC4near-gene-50.9891.014500.01130.19954
rs313604216:14014055T/CERCC4coding-synon,ncRNA0.7030.964060.04480.41384
rs313605116:14015252T/CERCC4intron0.9781.020510.02360.39015
rs313605516:14015577C/GERCC4intron0.9670.982060.02100.38947
rs313605616:14015932T/CERCC4coding-synon,ncRNA0.6090.995010.05680.92997
rs313606416:14017381T/CERCC4intron0.9871.016030.01120.15637
rs313606516:14017448A/GERCC4intron0.9851.016030.01120.15716
rs313606616:14017465C/GERCC4intron0.8191.011060.03440.74987
rs313606716:14017559T/CERCC4intron0.9750.986690.01180.25466
rs313607016:14017719A/TERCC4intron0.9740.986390.01130.22372b
rs313607316:14017841A/GERCC4intron0.9831.019180.02350.41882b
rs313607916:14019237T/GERCC4intron0.9800.988270.01180.31566
rs313608516:14019581C/GERCC4intron0.9811.011470.01180.33315
rs313609916:14023005T/CERCC4intron0.9850.976580.02320.3077
rs313610516:14023521T/CERCC4intron0.9870.978630.02320.35197
rs313610616:14023561A/GERCC4intron0.6000.965410.04680.45217
rs313611216:14024407T/CERCC4intron0.9871.017040.01130.13316
rs313615516:14030360T/CERCC4intron0.9891.017350.01130.1295
rs313616016:14031063A/GERCC4intron0.9981.020200.01120.072787
rs313616516:14031905A/GERCC4intron,near-gene-30.8191.037900.04740.43275
rs313616616:14032093T/GERCC4intron1.0000.982460.01110.11226
rs313616816:14032454T/GERCC4intron1.0000.982360.01110.10875
rs313617116:14032756T/CERCC4intron0.9071.012580.03310.70577
rs313617216:14032876A/GERCC4intron0.9980.987870.01170.29727
rs313617316:14033067T/GERCC4intron0.9971.012380.01170.29367
rs313617616:14033296A/TERCC4intron0.9960.987780.01170.29187
rs313618316:14034239A/GERCC4intron0.9861.017450.02360.46475
rs313618716:14034499A/GERCC4intron0.9980.987780.01170.29115
rs313618916:14034701T/CERCC4intron0.9970.986890.01170.26033a
rs313619416:14036334T/CERCC4intron0.9871.017250.02360.46937
rs313619516:14036471T/CERCC4intron0.9920.987280.02350.58676
rs313620216:14038174A/GERCC4intron0.9991.020000.01120.076437
rs313620316:14038201A/GERCC4intron0.7900.972490.04650.54916
rs313620816:14039439C/GERCC4intron0.9890.987380.02350.58957
rs313621116:14039648C/GERCC4intron0.9950.986100.01170.23135
rs313621316:14040153T/CERCC4intron0.9951.015320.01170.19615
rs313621516:14040282T/CERCC4intron0.6761.047700.03240.15027
rs313621616:14040351T/CERCC4intron0.9881.014710.02350.53417
rs313621816:14040598T/GERCC4intron0.9930.984520.01120.16336
rs313621916:14040722A/TERCC4intron0.9950.986990.01170.2627
rs313622016:14040910T/CERCC4intron0.6730.987780.03580.73127
rs378487216:14046264T/CERCC4near-gene-30.9930.985600.01180.21796
rs478156216:14045236T/GERCC4ncRNA,untranslated-30.9941.016130.01170.1745
rs478156316:14045399A/GERCC4ncRNA,untranslated-30.9941.015110.01180.20245
rs649848616:14013666A/CERCC4near-gene-50.9880.990640.01180.42482b
rs7278146816:14043260A/GERCC4ncRNA,untranslated-30.6030.951420.06860.46856
rs7278147216:14046673T/CERCC4near-gene-30.6020.949900.06880.45477
rs74415416:14015081C/GERCC4intron0.9851.010450.01190.38017
rs7644772316:14043625T/GERCC4ncRNA,untranslated-30.9831.016430.02370.49166
rs7956097216:14045697T/CERCC4ncRNA,untranslated-30.9820.987280.02360.58767
rs95707816:14019704T/GERCC4intron0.9700.990350.01170.40625
rs992550916:14044378A/GERCC4ncRNA,untranslated-30.9860.983930.02350.49027
SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*

  Note: RegulomeDB score*
score supporting data score supporting data
1aeQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak6other
2aTF binding + matched TF motif + matched DNase Footprint + DNase peak5TF binding or DNase peak
1beQTL + TF binding + any motif + DNase Footprint + DNase peak4TF binding + DNase peak
2bTF binding + any motif + DNase Footprint + DNase peak3bTF binding + matched TF motif
1ceQTL + TF binding + matched TF motif + DNase peak1feQTL + TF binding / DNase peak
2cTF binding + matched TF motif + DNase peak3aTF binding + any motif + DNase peak
1deQTL + TF binding + any motif + DNase peak1eeQTL + TF binding + matched TF motif
CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation
KEGG pathway annotationhsa03420; Nucleotide excision repair
KEGG pathway annotationhsa03460; Fanconi anemia pathway
GO annotation
GO pathway annotationGO:0000014; single-stranded DNA endodeoxyribonuclease activity
GO pathway annotationGO:0000109; nucleotide-excision repair complex
GO pathway annotationGO:0000110; nucleotide-excision repair factor 1 complex
GO pathway annotationGO:0000712; resolution of meiotic recombination intermediates
GO pathway annotationGO:0000723; telomere maintenance
GO pathway annotationGO:0000724; double-strand break repair via homologous recombination
GO pathway annotationGO:0000781; chromosome, telomeric region
GO pathway annotationGO:0000784; nuclear chromosome, telomeric region
GO pathway annotationGO:0001094; TFIID-class transcription factor binding
GO pathway annotationGO:0003684; damaged DNA binding
GO pathway annotationGO:0003697; single-stranded DNA binding
GO pathway annotationGO:0004520; endodeoxyribonuclease activity
GO pathway annotationGO:0005515; protein binding
GO pathway annotationGO:0005634; nucleus
GO pathway annotationGO:0005654; nucleoplasm
GO pathway annotationGO:0005669; transcription factor TFIID complex
GO pathway annotationGO:0006281; DNA repair
GO pathway annotationGO:0006283; transcription-coupled nucleotide-excision repair
GO pathway annotationGO:0006289; nucleotide-excision repair
GO pathway annotationGO:0006295; nucleotide-excision repair, DNA incision, 3'-to lesion
GO pathway annotationGO:0006296; nucleotide-excision repair, DNA incision, 5'-to lesion
GO pathway annotationGO:0006302; double-strand break repair
GO pathway annotationGO:0008022; protein C-terminus binding
GO pathway annotationGO:0009411; response to UV
GO pathway annotationGO:0009650; UV protection
GO pathway annotationGO:0032205; negative regulation of telomere maintenance
GO pathway annotationGO:0033683; nucleotide-excision repair, DNA incision
GO pathway annotationGO:0034644; cellular response to UV
GO pathway annotationGO:0036297; interstrand cross-link repair
GO pathway annotationGO:0043566; structure-specific DNA binding
GO pathway annotationGO:0047485; protein N-terminus binding
GO pathway annotationGO:0070522; ERCC4-ERCC1 complex
GO pathway annotationGO:0070911; global genome nucleotide-excision repair
GO pathway annotationGO:1901255; nucleotide-excision repair involved in interstrand cross-link repair
Co-expression Information

There is no gene co-express this gene!

Expression pattern
Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction