DRD3

Basic Information
Gene SymbolDRD3
Entrez Id1814
Positionchr3:113847557..113897899
Descriptiondopamine receptor D3
Gene typeprotein-coding
SNP Information

SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*
rs109342563:113885652A/CDRD3intron0.9941.015720.01330.23916
rs1112348433:113895344T/CDRD3intron0.9900.986100.03520.68987
rs1112482543:113883058A/CDRD3intron0.9871.015620.01210.20087
rs1115224453:113884092T/CDRD3intron0.9931.006220.02250.78387
rs1115384593:113915910T/CDRD3intron0.9490.973560.02230.22937
rs1116871983:113912154A/CDRD3intron0.9591.001800.01990.92886
rs1121157123:113876873T/CDRD3intron0.9771.008230.02270.71736
rs1123295023:113899283A/GDRD3intron,near-gene-50.9891.023980.02270.29617
rs1125290013:113885965T/CDRD3intron0.9931.008740.02250.69737
rs1127180543:113884963T/GDRD3intron0.9920.991730.02250.71086
rs1127705013:113880350A/CDRD3intron0.9981.015210.03500.66727
rs1129153693:113901605T/CDRD3intron0.9910.976770.02260.29947
rs1129769683:113903568A/TDRD3intron0.6521.053800.04810.27577
rs1130291863:113888024A/TDRD3intron0.9931.008540.02250.70366
rs1130521313:113916415T/CDRD3intron0.6510.946960.04820.2587
rs1133250913:113892336A/CDRD3intron,near-gene-50.9911.004310.02250.84765
rs1135083083:113912057T/CDRD3intron0.9720.983930.02690.54716
rs1137056763:113913179A/GDRD3intron0.9950.981870.02820.51616
rs1137393073:113913139A/TDRD3intron0.9950.981870.02820.51616
rs1142076313:113874531A/GDRD3intron0.8871.011060.05400.83854
rs1142992703:113889771T/CDRD3intron0.8161.035620.04990.48387
rs1151952533:113881907A/GDRD3intron0.9380.960980.03990.31886
rs1154853683:113912213A/TDRD3intron0.7080.985410.03970.71057
rs1158526603:113915315A/CDRD3intron0.8210.936600.03070.033197
rs1158700083:113885955A/CDRD3intron0.8160.965410.04990.48067
rs119215003:113861142A/GDRD3intron0.9960.985010.03490.66417
rs119291083:113861121A/CDRD3intron0.9271.010860.03400.75016
rs124875483:113857002T/CDRD3intron0.6560.986100.01870.45347
rs124909223:113856881A/TDRD3intron0.7991.028810.02920.33026
rs124951903:113916804C/GDRD3intron0.9931.018160.02820.52277
rs126336073:113903605A/GDRD3intron0.9930.972100.01410.044337
rs126336303:113903704A/CDRD3intron0.9950.980000.01300.12027
rs130613363:113854855A/GDRD3intron0.8760.963580.04010.35546
rs130688073:113856705T/CDRD3intron0.9110.999200.01230.94815
rs13543483:113906226A/CDRD3intron0.9780.972190.02690.29535
rs1387959883:113856620T/CDRD3intron0.9540.977750.02880.4354-
rs1413530033:113854698A/GDRD3intron0.7711.038420.04430.3947-
rs1414468623:113858864A/GDRD3intron0.9000.933050.05220.1842-
rs1417972913:113884676A/GDRD3intron0.8031.047600.04200.2681-
rs1424235433:113906851T/CDRD3intron0.8040.894670.04660.0169-
rs1433493683:113879538A/TDRD3intron0.9590.976970.05320.661-
rs1450320643:113894420A/TDRD3intron0.8220.930340.05200.165-
rs1496424803:113871077A/GDRD3intron0.9270.994810.05320.9218-
rs15877563:113902751T/CDRD3intron0.9930.972190.01410.044547
rs15877573:113902835A/GDRD3intron0.9920.971810.01410.042126
rs15877583:113903025A/GDRD3intron0.9930.972190.01410.044497
rs1677703:113879562A/GDRD3intron0.9990.987680.01170.28827
rs1677713:113876275A/GDRD3intron0.9901.001000.01400.94545
rs168224163:113890310A/GDRD3intron0.9931.001400.02240.94887
rs176055343:113911571A/CDRD3intron0.9970.982060.02820.52177
rs176056083:113912270A/GDRD3intron0.9921.020710.01300.11527
rs176685243:113906855T/CDRD3intron0.9871.019590.02820.49017
rs176686943:113914682A/GDRD3intron0.9940.981960.02820.51977
rs18008273:113891185T/CDRD3intron,near-gene-50.9960.990740.03460.78877
rs18008283:113891549C/GDRD3intron,near-gene-50.9970.986590.01230.27386
rs1898093163:113911929A/GDRD3intron0.7460.977070.04330.5918-
rs1931560923:113854347T/CDRD3intron0.7081.031380.03040.3094-
rs19614623:113857277A/GDRD3intron0.9500.994020.01260.63597
rs21346553:113858201T/CDRD3intron0.9720.988270.01200.32677
rs23995013:113875861A/CDRD3intron0.7340.981180.01770.28376
rs26303473:113868386A/GDRD3intron0.9911.003410.01600.83035
rs26303493:113873372A/GDRD3intron0.9911.019080.02190.38884
rs26303503:113874996T/CDRD3intron0.9901.016940.02220.44885
rs26303513:113875059A/GDRD3intron0.9901.019280.02220.38815
rs26547543:113855796A/GDRD3intron0.9871.010560.03420.75816
rs284197453:113859302A/GDRD3intron0.9971.014910.03490.67077
rs29712093:113884136T/CDRD3intron0.9491.010660.01170.3667
rs29715693:113884137T/GDRD3intron0.9520.986990.01120.24297
rs3240223:113887298A/GDRD3intron1.0001.011870.01170.31145
rs3240233:113885395T/CDRD3intron1.0001.012680.01170.28037
rs3240263:113891042T/CDRD3intron,near-gene-51.0000.988760.01120.31267
rs3240283:113893343A/GDRD3intron0.9930.988960.01120.32516
rs3240293:113881623A/GDRD3intron1.0001.012170.01170.29887
rs3240303:113881441C/GDRD3intron1.0000.987680.01170.28947
rs3240313:113878001T/CDRD3intron0.9830.977260.02200.29586
rs3240323:113877828A/GDRD3intron0.9840.979320.02210.34455
rs3240333:113876743A/CDRD3intron0.9780.994120.01670.72537
rs3240353:113868854A/CDRD3intron0.9850.998800.01370.93087
rs3240363:113867862C/GDRD3intron0.9911.002500.01600.87477
rs340086053:113898525C/GDRD3intron,near-gene-50.9820.996900.02220.893a
rs348049423:113897452T/CDRD3intron0.9661.034480.04410.44256
rs362117963:113892886A/TDRD3intron0.9901.004310.02250.84686
rs362117983:113893087T/CDRD3intron0.9901.004410.02250.84586
rs362118003:113897085T/CDRD3intron0.9831.053270.03370.1245
rs362118023:113897573T/CDRD3near-gene-5,untranslated-50.9851.023780.02270.30257
rs362121753:113897801T/CDRD3intron,near-gene-5,untranslated-50.9821.004510.02220.83814
rs362121773:113898814A/GDRD3intron,near-gene-50.9820.996900.02220.89045
rs362121783:113902608A/GDRD3intron0.9930.971420.01410.039076
rs362121823:113902902T/CDRD3intron0.9761.028700.02700.29437
rs362125143:113903081A/GDRD3intron0.9991.018160.02820.5237
rs362125153:113903248T/CDRD3intron0.9930.972190.01410.044476
rs362125163:113905934A/GDRD3intron0.9880.996410.02600.89137
rs362125173:113906211T/CDRD3intron0.8590.957620.05150.40015
rs45929963:113850489T/CDRD3intron0.9760.994220.03420.86497
rs46469963:113849565T/CDRD3intron0.9761.005920.01060.57817
rs579282793:113914010A/TDRD3intron0.9911.022350.02260.32727
rs581921323:113906974A/GDRD3intron1.0001.018160.02820.52387
rs586000143:113915817A/CDRD3intron0.8400.986000.01880.45176
rs594932683:113905040T/CDRD3intron0.9920.971900.01410.04296
rs603428113:113913846T/CDRD3intron0.9921.022760.02260.31963a
rs605850233:113903843T/CDRD3intron0.9991.018160.02820.52346
rs607304513:113887477A/GDRD3intron0.9941.016230.01330.22396
rs615956103:113888312C/GDRD3intron0.9961.008840.03460.79957
rs622671273:113860890C/GDRD3intron0.8611.036140.02950.22896
rs622671523:113884781C/GDRD3intron0.9911.014610.01330.27547
rs622671543:113901103C/GDRD3intron0.9931.028810.01410.043567
rs622689613:113916202A/GDRD3intron0.9890.969480.01390.025456
rs622689623:113917372A/TDRD3intron0.9920.978140.01280.085647
rs62803:113890815T/CDRD3missense1.0000.988760.01120.31325
rs67951883:113860915A/GDRD3intron0.9061.019590.02010.3356
rs68010683:113910116C/GDRD3intron0.9970.985700.01110.19677
rs68062173:113889069A/GDRD3intron0.9961.006120.03470.86027
rs716536273:113878467A/GDRD3intron0.9870.998300.02530.94526
rs729446983:113893820A/GDRD3intron0.9931.009550.03470.78317
rs729466143:113910958T/CDRD3intron0.9960.996810.02550.89966
rs732325693:113850332A/GDRD3intron0.9440.966860.03940.39277
rs732359063:113911544T/CDRD3intron0.7770.975700.03400.46957
rs732359083:113915496T/CDRD3intron0.9181.031280.03810.41936
rs738562673:113911022T/CDRD3intron0.9961.003210.02550.89997
rs744430903:113907049T/CDRD3intron0.9931.022960.02070.2716
rs745134903:113892585A/TDRD3intron,near-gene-50.9901.005920.02240.79177
rs749889703:113899423T/CDRD3intron,near-gene-50.9820.996900.02220.88937
rs750097403:113885354T/CDRD3intron0.7221.008130.04090.84287
rs753757753:113914791A/CDRD3intron0.9851.051060.03330.13457
rs754794233:113913448C/GDRD3intron0.9970.996410.02580.88976
rs757722923:113917438T/CDRD3intron0.9921.022350.02260.32867
rs758119523:113899126A/CDRD3intron,near-gene-50.9820.997000.02220.89166
rs758591273:113885417A/GDRD3intron0.9881.000800.02530.9747
rs759706393:113900740T/CDRD3intron0.9950.979610.02060.31726
rs759826483:113849751A/GDRD3intron0.9790.991240.01900.64386
rs761296343:113914976A/TDRD3intron0.9851.051170.03330.13446
rs761328333:113887728T/CDRD3intron0.9931.008640.02250.70257
rs76388763:113894300T/CDRD3intron1.0000.987080.01120.24227
rs764576373:113916352A/GDRD3intron0.9910.978140.02260.3286
rs764598083:113895029T/CDRD3intron,untranslated-50.9890.995810.02250.85116
rs764658293:113887264T/CDRD3intron0.7791.033650.02660.21375
rs765972983:113880461T/GDRD3intron0.9791.084800.05080.10947
rs766179383:113916769A/GDRD3intron0.9921.022350.02260.32847
rs770681303:113910834T/CDRD3intron0.9981.018260.02820.52215
rs773483123:113872272A/GDRD3intron0.9790.952850.04590.29277
rs774891113:113881802T/CDRD3intron0.9931.006220.02250.78317
rs778442343:113910626A/TDRD3intron0.9961.002200.01580.88647
rs781088163:113908389T/CDRD3intron0.9911.021940.02250.33547
rs786227843:113859487A/GDRD3intron0.8621.074550.02940.014567
rs787900933:113899913A/GDRD3intron0.9891.002200.02610.93147
rs788415383:113849885T/CDRD3intron0.8190.958390.04870.38276
rs789113743:113915977A/TDRD3intron0.9720.985210.02800.5936
rs789132893:113911807A/TDRD3intron0.9740.954950.03300.16316
rs794317743:113905115T/CDRD3intron0.9940.978240.02060.28666
rs794502203:113912178A/GDRD3intron0.9901.000900.01900.96097
rs796262503:113894684A/TDRD3intron0.9800.951320.03320.13267
rs801028773:113888553T/CDRD3intron0.9030.940730.04800.20357
rs92835603:113912235A/GDRD3intron0.9960.996710.02550.89627
rs92889913:113855761C/GDRD3intron0.9881.016330.03400.6346
rs92889923:113859137A/GDRD3intron0.9960.982650.03510.6187
rs92889933:113859173A/GDRD3intron0.9971.014300.03490.68277
rs9634683:113862887A/GDRD3intron0.9810.991930.01090.45455
rs98113263:113884979T/CDRD3intron0.9960.990840.03460.79137
rs98136333:113908226A/CDRD3intron1.0001.010250.02760.71327
rs98248563:113852731A/CDRD3intron0.9851.011260.03430.74477
rs98255633:113900220A/GDRD3intron0.9970.980690.01150.088326
rs98280463:113858263A/GDRD3intron0.9790.981080.03490.58376
rs98375243:113856611T/GDRD3intron0.9871.015930.03450.64657
rs98454173:113849111A/GDRD3intron0.9761.005920.01070.58086
rs98597623:113857118A/GDRD3intron0.9881.013690.03440.69337
rs98714723:113883867A/GDRD3intron0.9961.009340.03460.78717
rs98730533:113868419T/CDRD3intron0.9941.020710.03510.5595
rs98785693:113848416A/GDRD3intron0.9930.983050.03510.62635
rs98801683:113866551A/GDRD3intron0.9871.011360.01700.50657
rs98804943:113903791A/GDRD3intron0.9971.014710.01110.19117
rs98813813:113915783T/CDRD3intron0.9961.006620.02560.7967
SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*

  Note: RegulomeDB score*
score supporting data score supporting data
1aeQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak6other
2aTF binding + matched TF motif + matched DNase Footprint + DNase peak5TF binding or DNase peak
1beQTL + TF binding + any motif + DNase Footprint + DNase peak4TF binding + DNase peak
2bTF binding + any motif + DNase Footprint + DNase peak3bTF binding + matched TF motif
1ceQTL + TF binding + matched TF motif + DNase peak1feQTL + TF binding / DNase peak
2cTF binding + matched TF motif + DNase peak3aTF binding + any motif + DNase peak
1deQTL + TF binding + any motif + DNase peak1eeQTL + TF binding + matched TF motif
CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation
KEGG pathway annotationhsa04080; Neuroactive ligand-receptor interaction
KEGG pathway annotationhsa04728; Dopaminergic synapse
GO annotation
GO pathway annotationGO:0000122; negative regulation of transcription from RNA polymerase II promoter
GO pathway annotationGO:0001588; dopamine neurotransmitter receptor activity, coupled via Gs
GO pathway annotationGO:0001591; dopamine neurotransmitter receptor activity, coupled via Gi/Go
GO pathway annotationGO:0001963; synaptic transmission, dopaminergic
GO pathway annotationGO:0001975; response to amphetamine
GO pathway annotationGO:0002016; regulation of blood volume by renin-angiotensin
GO pathway annotationGO:0002031; G-protein coupled receptor internalization
GO pathway annotationGO:0005515; protein binding
GO pathway annotationGO:0005886; plasma membrane
GO pathway annotationGO:0005887; integral component of plasma membrane
GO pathway annotationGO:0006874; cellular calcium ion homeostasis
GO pathway annotationGO:0007186; G-protein coupled receptor signaling pathway
GO pathway annotationGO:0007191; adenylate cyclase-activating dopamine receptor signaling pathway
GO pathway annotationGO:0007194; negative regulation of adenylate cyclase activity
GO pathway annotationGO:0007195; adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO pathway annotationGO:0007611; learning or memory
GO pathway annotationGO:0007612; learning
GO pathway annotationGO:0007626; locomotory behavior
GO pathway annotationGO:0008144; drug binding
GO pathway annotationGO:0008284; positive regulation of cell proliferation
GO pathway annotationGO:0008542; visual learning
GO pathway annotationGO:0014059; regulation of dopamine secretion
GO pathway annotationGO:0019216; regulation of lipid metabolic process
GO pathway annotationGO:0019904; protein domain specific binding
GO pathway annotationGO:0030139; endocytic vesicle
GO pathway annotationGO:0030814; regulation of cAMP metabolic process
GO pathway annotationGO:0031748; D1 dopamine receptor binding
GO pathway annotationGO:0032416; negative regulation of sodium:proton antiporter activity
GO pathway annotationGO:0032467; positive regulation of cytokinesis
GO pathway annotationGO:0032922; circadian regulation of gene expression
GO pathway annotationGO:0034776; response to histamine
GO pathway annotationGO:0035176; social behavior
GO pathway annotationGO:0035240; dopamine binding
GO pathway annotationGO:0035483; gastric emptying
GO pathway annotationGO:0035815; positive regulation of renal sodium excretion
GO pathway annotationGO:0040014; regulation of multicellular organism growth
GO pathway annotationGO:0042220; response to cocaine
GO pathway annotationGO:0042417; dopamine metabolic process
GO pathway annotationGO:0042493; response to drug
GO pathway annotationGO:0042995; cell projection
GO pathway annotationGO:0043278; response to morphine
GO pathway annotationGO:0045177; apical part of cell
GO pathway annotationGO:0045187; regulation of circadian sleep/wake cycle, sleep
GO pathway annotationGO:0045471; response to ethanol
GO pathway annotationGO:0045776; negative regulation of blood pressure
GO pathway annotationGO:0045840; positive regulation of mitotic nuclear division
GO pathway annotationGO:0045944; positive regulation of transcription from RNA polymerase II promoter
GO pathway annotationGO:0046717; acid secretion
GO pathway annotationGO:0048148; behavioral response to cocaine
GO pathway annotationGO:0048715; negative regulation of oligodendrocyte differentiation
GO pathway annotationGO:0050482; arachidonic acid secretion
GO pathway annotationGO:0050709; negative regulation of protein secretion
GO pathway annotationGO:0050883; musculoskeletal movement, spinal reflex action
GO pathway annotationGO:0051584; regulation of dopamine uptake involved in synaptic transmission
GO pathway annotationGO:0051898; negative regulation of protein kinase B signaling
GO pathway annotationGO:0060134; prepulse inhibition
GO pathway annotationGO:0060160; negative regulation of dopamine receptor signaling pathway
GO pathway annotationGO:0060161; positive regulation of dopamine receptor signaling pathway
GO pathway annotationGO:0090325; regulation of locomotion involved in locomotory behavior
Co-expression Information

There is no gene co-express this gene!

Expression pattern
Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction