CSF2RB

Basic Information
Gene SymbolCSF2RB
Entrez Id1439
Positionchr22:37309675..37336481
Descriptioncolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Gene typeprotein-coding
SNP Information

SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*
rs1022223222:37317970A/GCSF2RBintron0.9980.976680.01050.024535
rs1022223822:37318014T/GCSF2RBintron0.9981.023880.01050.024565
rs1108981022:37323638T/CCSF2RBintron0.9251.010560.01870.57375
rs11213767522:37333109T/GCSF2RBintron0.6060.968020.03130.29955
rs11461318922:37325148A/GCSF2RBintron0.8300.970060.04360.48652b
rs11505406622:37320500T/CCSF2RBintron0.7541.022450.03420.51615
rs11685718622:37321973T/CCSF2RBintron0.7930.978930.02570.40855
rs11751188022:37328051A/GCSF2RBintron0.7941.014000.03770.71315
rs11759637422:37312311C/GCSF2RBintron0.8901.005920.06140.92333a
rs11764809322:37309959A/GCSF2RBintron0.7331.031180.05060.54375
rs11768949022:37318121T/GCSF2RBuntranslated-50.9141.031790.03600.3845
rs11769786622:37308572C/GCSF2RBnear-gene-50.9210.965700.03650.33975
rs11780530822:37326794A/GCSF2RBmissense0.7431.009550.04820.8434
rs11793723322:37318175T/CCSF2RBuntranslated-50.9141.025420.02700.35295
rs1191314822:37312745T/CCSF2RBintron0.9100.976090.03560.49766
rs1262849522:37307711T/CCSF2RBnear-gene-50.9741.017860.01700.29966
rs1305487722:37321782C/GCSF2RBintron0.8310.999200.02190.97275
rs13184222:37335773A/GCSF2RBuntranslated-30.9361.029120.01450.047256
rs14748236422:37328425T/CCSF2RBintron0.7971.013690.03750.7174-
rs153487922:37328966C/GCSF2RBintron0.9591.024800.01090.024185
rs153488022:37329111C/GCSF2RBintron0.9591.025620.01090.020295
rs153488122:37329448A/GCSF2RBintron0.9671.025110.01080.0225
rs153488222:37329545A/GCSF2RBintron0.9240.979610.01240.096945
rs1698556422:37317550T/CCSF2RBintron0.6321.039350.05620.49264
rs1699749222:37307865T/CCSF2RBnear-gene-50.9191.031900.03650.38895
rs1699749522:37308516T/CCSF2RBnear-gene-50.8970.955810.03490.19535
rs1699749822:37308691T/CCSF2RBnear-gene-50.9841.021730.01470.14275
rs1699750722:37324090A/GCSF2RBintron0.8420.967050.04300.43525
rs1699751022:37333406T/GCSF2RBintron0.9070.998100.03860.96165
rs1699751722:37333936T/CCSF2RBnear-gene-3,missense0.9390.990940.04240.83085
rs1781136522:37322820T/GCSF2RBintron0.9370.988070.01860.51843a
rs180111422:37333804A/GCSF2RBnear-gene-3,missense0.9140.998200.04150.96515
rs180111622:37334250A/GCSF2RBcoding-synon0.8001.020610.03890.59935
rs180111722:37329999T/CCSF2RBcoding-synon0.9000.985010.01360.26755
rs180112222:37333657A/CCSF2RBnear-gene-3,missense0.6460.975700.03550.48745
rs180754422:37311219T/CCSF2RBintron0.9821.021320.01060.046827
rs18234287222:37324857T/CCSF2RBintron0.6941.002600.05160.9595-
rs204990822:37311089A/GCSF2RBintron0.9910.978630.01060.040237
rs207270722:37319081T/GCSF2RBintron0.9430.967440.01160.004175
rs207271322:37319425T/GCSF2RBintron0.9511.022350.01080.040145
rs207572422:37309418T/GCSF2RBnear-gene-50.9751.012480.01070.24855
rs207572522:37309916A/GCSF2RBintron0.9821.015520.01070.14975
rs207572622:37310046A/GCSF2RBintron0.9641.016540.01070.1265
rs207572722:37310217T/CCSF2RBintron0.9831.018980.01070.077693a
rs207593622:37328751A/GCSF2RBintron0.9500.976870.01090.032125
rs207593722:37330082T/CCSF2RBintron0.9720.974820.01080.018375
rs207594022:37318446A/GCSF2RBintron0.9851.024190.01060.023964
rs207594122:37318515T/CCSF2RBintron0.9820.976190.01060.023152b
rs207594222:37318779T/CCSF2RBintron0.9600.975020.01070.018475
rs207594322:37319009A/GCSF2RBintron0.9571.021220.01080.050915
rs217905122:37330721T/CCSF2RBintron0.9051.026850.01260.035935
rs223974922:37331305A/GCSF2RBintron0.9640.975900.01080.024355
rs228097622:37318426T/CCSF2RBintron0.9831.023570.01060.027694
rs228403022:37320873T/CCSF2RBintron0.8480.958680.01280.0010175
rs228403122:37321080T/CCSF2RBintron0.9200.977360.01110.038795
rs241343522:37312264T/GCSF2RBintron0.9971.022650.01050.033094
rs241343622:37312561A/GCSF2RBintron0.9970.978040.01050.034617
rs383391622:37332003I2/DCSF2RBintron0.9470.973850.01090.01497-
rs4128000522:37316133A/GCSF2RBintron0.9601.011470.01420.42317
rs4128000722:37317914T/CCSF2RBintron0.9121.020810.02670.44215
rs4128000922:37318033T/CCSF2RBintron0.7641.035720.02930.23115
rs4128322522:37334659A/GCSF2RBuntranslated-30.7580.943460.03580.10435
rs4129724722:37331607A/GCSF2RBintron0.9211.002200.04370.95925
rs423988222:37314008A/GCSF2RBintron0.9980.977750.01050.032246
rs433904722:37328968C/GCSF2RBintron0.8630.987180.01410.35795
rs443706422:37319947C/GCSF2RBintron0.9300.978040.01090.041455
rs458356422:37308915T/GCSF2RBnear-gene-50.9771.011870.01070.2697
rs482026122:37316949A/GCSF2RBintron0.9991.024600.01050.020985
rs482026222:37317109T/CCSF2RBintron0.9990.976090.01050.020994
rs482155822:37308785T/CCSF2RBnear-gene-50.9830.975990.01470.097175
rs482155922:37310269T/CCSF2RBintron0.9800.983140.01070.11023a
rs482156022:37311806T/GCSF2RBintron0.9890.979020.01060.045127
rs482156122:37311877T/CCSF2RBintron0.9921.022040.01060.039086
rs482156222:37314179A/TCSF2RBintron0.9720.964740.01180.0023796
rs482156322:37314185A/CCSF2RBintron0.9720.964740.01180.0023816
rs482156422:37314290T/CCSF2RBintron0.9720.963580.01190.0018367
rs482156522:37314415T/CCSF2RBintron0.9980.978340.01050.037726
rs482156622:37314507C/GCSF2RBintron0.9980.977750.01050.032597
rs482156722:37316388T/GCSF2RBintron1.0000.975700.01050.018925
rs482156822:37316476T/CCSF2RBintron1.0000.976290.01050.022116
rs482156922:37316873A/GCSF2RBintron0.9990.975900.01050.020425
rs482157022:37317177C/GCSF2RBintron0.9990.976090.01050.0215
rs6017541122:37311858A/GCSF2RBintron0.9581.011260.01420.42886
rs6222909722:37314001A/GCSF2RBintron0.9600.981380.01510.21226
rs6655407422:37317029I5/DCSF2RBintron0.9840.974630.01060.01529-
rs7216646722:37323520D/I3CSF2RBintron0.9271.010150.01870.5889-
rs729243022:37333367A/GCSF2RBintron0.7220.883110.04770.0092415
rs7315815622:37327979A/GCSF2RBintron0.7250.998000.03700.95715
rs7315816022:37329339A/GCSF2RBintron0.7611.001700.03520.96195
rs7315816322:37332207A/GCSF2RBintron0.7580.996510.03540.92035
rs7388397322:37307840T/CCSF2RBnear-gene-50.9190.969090.03650.38885
rs7388397422:37309807A/GCSF2RBintron0.9250.969570.03620.39414
rs7470129822:37324740T/CCSF2RBintron0.8291.027780.04330.52724
rs7593249022:37330500T/GCSF2RBintron0.8020.991540.03700.81825
rs7621823322:37315884T/CCSF2RBintron0.9171.032520.03590.3737
rs7712184322:37314600A/GCSF2RBintron0.9221.025620.02700.34987
rs7729441922:37310314C/GCSF2RBintron0.9271.034480.03600.34584
rs7781118722:37329636A/GCSF2RBintron0.7411.020610.04460.64675
rs7781886322:37312301A/GCSF2RBintron0.9030.951610.03010.099643a
rs7799133222:37310755I2/DCSF2RBintron0.9591.019790.01510.1942-
rs7841896122:37313996A/GCSF2RBintron0.9171.031490.03590.38797
rs7857491422:37330074T/CCSF2RBintron0.8041.008130.03700.82665
rs7903775922:37315967A/GCSF2RBintron0.7391.012880.03610.72355
rs8011330622:37322660T/GCSF2RBintron0.8340.974630.04470.5655
rs90948622:37323988T/CCSF2RBintron1.0001.020810.01070.053235
rs960739022:37314533T/CCSF2RBintron0.9971.022760.01050.032217
rs960739122:37314770A/TCSF2RBintron0.9980.977750.01050.032567
rs960739222:37315592T/CCSF2RBintron0.9981.022760.01050.032296
rs960739322:37315700A/GCSF2RBintron0.9470.980590.01080.069257
rs960739422:37315733A/GCSF2RBintron0.9241.034070.01200.0051697
rs960739522:37315742T/CCSF2RBintron0.9691.020000.01070.062847
rs960739622:37315912A/CCSF2RBintron0.9981.022760.01050.032087
rs960739722:37315988T/CCSF2RBintron0.9991.023060.01050.029885
rs960739822:37316041T/CCSF2RBintron0.9981.023160.01050.0295
rs961060622:37315667A/GCSF2RBintron0.9601.021320.01070.048857
rs961060722:37315759T/CCSF2RBintron0.9970.977750.01050.032316
SNPPositionAlelleGeneAnnotationInfoOrSeP-valueeQTLScore*

  Note: RegulomeDB score*
score supporting data score supporting data
1aeQTL + TF binding + matched TF motif + matched DNase Footprint + DNase peak6other
2aTF binding + matched TF motif + matched DNase Footprint + DNase peak5TF binding or DNase peak
1beQTL + TF binding + any motif + DNase Footprint + DNase peak4TF binding + DNase peak
2bTF binding + any motif + DNase Footprint + DNase peak3bTF binding + matched TF motif
1ceQTL + TF binding + matched TF motif + DNase peak1feQTL + TF binding / DNase peak
2cTF binding + matched TF motif + DNase peak3aTF binding + any motif + DNase peak
1deQTL + TF binding + any motif + DNase peak1eeQTL + TF binding + matched TF motif
CNV Information

The gene is not affected by CNV!

eQTL Information

There is no eQTL snp about this gene!

KEGG annotation
KEGG pathway annotationhsa04060; Cytokine-cytokine receptor interaction
KEGG pathway annotationhsa04210; Apoptosis
KEGG pathway annotationhsa04630; Jak-STAT signaling pathway
GO annotation
GO pathway annotationGO:0000165; MAPK cascade
GO pathway annotationGO:0000186; activation of MAPKK activity
GO pathway annotationGO:0004872; receptor activity
GO pathway annotationGO:0004912; interleukin-3 receptor activity
GO pathway annotationGO:0004914; interleukin-5 receptor activity
GO pathway annotationGO:0005515; protein binding
GO pathway annotationGO:0005622; intracellular
GO pathway annotationGO:0005886; plasma membrane
GO pathway annotationGO:0005887; integral component of plasma membrane
GO pathway annotationGO:0007165; signal transduction
GO pathway annotationGO:0007173; epidermal growth factor receptor signaling pathway
GO pathway annotationGO:0007264; small GTPase mediated signal transduction
GO pathway annotationGO:0007265; Ras protein signal transduction
GO pathway annotationGO:0007411; axon guidance
GO pathway annotationGO:0007585; respiratory gaseous exchange
GO pathway annotationGO:0008286; insulin receptor signaling pathway
GO pathway annotationGO:0008543; fibroblast growth factor receptor signaling pathway
GO pathway annotationGO:0030526; granulocyte macrophage colony-stimulating factor receptor complex
GO pathway annotationGO:0036016; cellular response to interleukin-3
GO pathway annotationGO:0038043; interleukin-5-mediated signaling pathway
GO pathway annotationGO:0038095; Fc-epsilon receptor signaling pathway
GO pathway annotationGO:0038156; interleukin-3-mediated signaling pathway
GO pathway annotationGO:0044267; cellular protein metabolic process
GO pathway annotationGO:0045087; innate immune response
GO pathway annotationGO:0048010; vascular endothelial growth factor receptor signaling pathway
GO pathway annotationGO:0048011; neurotrophin TRK receptor signaling pathway
Co-expression Information

There is no gene co-express this gene!

Expression pattern
Note: Avg - average expression of all genes
Description Age Description Age Description Age
Embryonic4-8 PCWEarly fetal18-10 PCWEarly fetal210-13 PCW
Early mid-fetal113-16 PCWEarly mid-fetal216-19 PCWLate mid-fetal19-24 PCW
Late fetal24-38 PCWNeonatal & early infancy0-6 MLate infancy6-12 M
Early childhood1-6 YMiddle and late childhood6-12 YAdolescence12-20 Y
Young adulthood20-40 YMiddle adulthood40-60 YLate adulthood60 Y+
Protein-protein interaction