Polygenic Risk Score (PRSice-2)


Step1: select a GWAS

CLOZUK             PGC2

Step2: upload genotype files

Plink binary bed file format
Plink binary bim file format
Plink binary fam file format
Example for genes
example.bed
example.bim
example.fam

Note

If you used this tool, please cite the reletive reference.
PGC2 GWAS: Schizophrenia Working Group of the Psychiatric Genomics Consortium. 2014. Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511(7510):421-427. [PMID: 25056061]
CLOZUK GWAS: Pardiñas et al. 2018. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 50(3):381-389. [PMID: 29483656]
PRSice-2: Choi et al. 2019. PRSice-2: Polygenic Risk Score Software for Biobank-Scale Data. GigaScience, 8(7):giz082. [PMID: 31307061]